正交试验优化妇康片的提取工艺

目的:优选妇康胶囊的最佳提取工艺。方法:采用正交试验设计,分别以蛇床子素、盐酸小檗碱提取率和浸膏收率为指标,优化黄连、蛇床子等6味药材的提取工艺;以没食子酸提取率和浸膏收率为指标,优选没食子等4味药材的提取工艺。结果:6味药材最佳提取工艺为:10倍量70%乙醇回流提取2次,每次1 h;没食子等4味药材最佳提取工艺为:10倍量水煎煮3次,每次1 h;结论:优选的提取工艺稳定、可行。

Optimization of Extraction Process for Fukang Tablets with Orthogonal Design

Objective: To optimize the extraction process of Fukang tablets. Method: Orthogonal design was used to optimize the extracting process of six herb medicines with the extract yield, the content of berberine hydrochloride and osthole as index;to optimize the extracting process of gallic and other two herb medicines with the extract yield and the content of gallic acid as index. Result: The optimum extraction progress was as follows:six herb medicines were extract 2 times for 1 hour with 10 times of 70% alcohol;gallic and other three herb medicines were extract 3 times for 1 hour with 10 times of water. Conclusion: The optimum extraction process was stable and feasible.