近60年中药毒副作用及不良反应文献分析

以"中药"和"毒性"或"毒副作用"或"副作用"或"不良反应"为检索词,系统检索"中国中医药期刊数据库"(1949-2007年)和"中国生物医学文献数据库"(2008年),收集第一手资料,建立不良反应数据库,对数据进行归纳分析后发现中药材和中药饮片的不良反应中,用药剂量过大、药物炮制不当或未经炮制、毒性药物使用不当、药材来源混淆或误用和其他药物使用不当,所占例数超过了总例数的90%。本结果为更好促进中药的国际化及其合理应用提供科学数据。

Literature Analysis on Toxicity,Side Effect and Adverse Reaction of Traditional Chinese Medicine

The Database of adverse reaction were set up according to the data from "The Traditional Chinese Medicine Database System (1949-2007)" and "The Chinese Biomedical Database System(2008)".The key words were concluding traditional Chinese medicine (TCM) and toxicity or side effect or adverse reaction.Studies showed there were over 90% of adverse reaction owing to overdose,improper or without processing,incorrect usage of toxic drug,the confused resource or misuse of medicinal plants.This result was a base for the research of internationalization and proper usage of TCM.