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正交法配合药效指标综合筛选木香切制工艺
引用本文:张旭,侯影,贾天柱.正交法配合药效指标综合筛选木香切制工艺[J].中国实验方剂学杂志,2011,17(7):9-12.
作者姓名:张旭  侯影  贾天柱
作者单位:辽宁中医药大学,辽宁省中药炮制工程技术研究中心,国家中医药管理局,中药炮制工艺原理重点研究室,辽宁,大连,116600
摘    要:目的:优选木香的最佳切制工艺。方法:以木香烃内酯含量、去氢木香内酯含量、小鼠小肠炭末推进率为测定指标,以浸润加水量、浸润时间、切片厚度为考察因素,采用L9(34)正交设计表,综合加权评分法确定木香饮片最佳切制工艺。结果:最佳切制工艺为:净木香药材加入0.3倍量水,浸润10 h后切成1~2 mm薄片。结论:木香的最佳切制工艺合理可行,可为规范木香饮片质量标准提供参考。

关 键 词:木香烃内酯  去氢木香内酯  小肠推进  切制工艺
收稿时间:2010/12/8 0:00:00

Optimization of Cutting Technology Associated with Pharmacodynamic Index for Aucklandiae Radix by Orthogonal Design
ZHANG Xu,HOU Ying and JIA Tian-zhu.Optimization of Cutting Technology Associated with Pharmacodynamic Index for Aucklandiae Radix by Orthogonal Design[J].China Journal of Experimental Traditional Medical Formulae,2011,17(7):9-12.
Authors:ZHANG Xu  HOU Ying and JIA Tian-zhu
Institution:Liaoning University of Traditional Chinese Medicine, Chinese Materia Medica Processing Engineering Center of Liaoning Province, Key Lab of Chinese Materia Medica Processing Principle of State Administration of Traditional Chinese Medicine, Dalian 116600, China;Liaoning University of Traditional Chinese Medicine, Chinese Materia Medica Processing Engineering Center of Liaoning Province, Key Lab of Chinese Materia Medica Processing Principle of State Administration of Traditional Chinese Medicine, Dalian 116600, China;Liaoning University of Traditional Chinese Medicine, Chinese Materia Medica Processing Engineering Center of Liaoning Province, Key Lab of Chinese Materia Medica Processing Principle of State Administration of Traditional Chinese Medicine, Dalian 116600, China
Abstract:Objective: to optimize the cutting technology of Aucklandiae Radix. Method: The cutting technology of Aucklandiae Radix was optimized by L9 (34) orthogonal design taking the content of costunolide and dehydrocostuslactone, the intestinal propulsion in mice as indexes with the amount of water, soaking time and thickness of pieces as factors. Result: The best cutting technology of Aucklandiae Radix was cutting 1-2 mm thin pieces after soaking 10 h with 0.3 times water. Conclusion: The optimum cutting technology of Aucklandiae Radix is reasonable and feasible; it can provide a reference for establishing the quality standard of Aucklandiae Radix pieces.
Keywords:costunolide  dehydrocostuslactone  intestinal propulsion  cutting technology
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