| 血府逐瘀合剂制备工艺研究 |
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| 引用本文： | 张平,刘志辉,刘汉清,钱芳.血府逐瘀合剂制备工艺研究[J].中国中医药信息杂志,2007,14(10):50-51. |
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| 作者姓名： | 张平 刘志辉 刘汉清 钱芳 |
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| 作者单位： | 1. 江苏省中医院中药制剂实验室,江苏,南京,210029:
2. 南京中医药大学,江苏,南京,210029 |
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| 摘 要： | 目的优选血府逐瘀合剂的制备工艺。方法以芍药苷含量为主要指标,干浸膏含量为参考指标,采用正交设计L9(34)优选血府逐瘀合剂的提取工艺;通过浓缩方法和浓缩程度考察浓缩工艺;以转速和时间为主要因素考察离心工艺。结果血府逐瘀合剂的最佳提取工艺为:加10倍量水浸泡1h,每次煎煮1h,煎煮2次;采用减压浓缩至相当于每1mL含1g原药材;采用4000r/min持续7min以上均可得到澄清药液。结论此制备工艺合理可行。
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| 关 键 词： | 血府逐瘀合剂 提取工艺 高效液相色谱法 芍药苷 |
| 文章编号： | 1005-5304（2007）10-0050-02 |
| 收稿时间： | 2007-03-09 |
| 修稿时间： | 2007年3月9日 |
Study on Preparation Process of Xuefuzhuyu Mixture |
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| ZHANG Ping, LIU Zhi-hui, LIU Han-qing, et al.Study on Preparation Process of Xuefuzhuyu Mixture[J].Chinese Journal of Information on Traditional Chinese Medicine,2007,14(10):50-51. |
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| Authors: | ZHANG Ping LIU Zhi-hui LIU Han-qing |
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| Institution: | (1.Laboratory of Traditional Chinese Medicine Preparation, Jiangsu Provincial Hospital of TCM, Nanjing 210029, China 2.Nanjing University of TCM, Nanfing 210029, China |
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| Abstract: | Objective To optimize the preparation process of Xuefuzhuyu Mixture. Methods Using the extracting rate of paeoniflorin as main indicator, the content of extracting as reference indicators, the extracting process was studied by L9(34) orthogonal method. Enrichment technique was reviewed by concentrated methods and levels. Centrifugal process was reviewed by speed and time. Results The optimum extracting procedure of Xuefuzhuyu Mixture was by 10 times of water soaking for 1 h, then decocting for 60 min and 2 times. Using decompressed enrichment, mixture was enriched 1 g herbs/1 mL. Clarify solution will be received if the condition up to 4 000 r/min and run more than 7 min. Conclusion The preparation process is reasonable and viable. |
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| Keywords: | Xuefuzhuyu Mixture extracting process HPLC Paeoniflorin |
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