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补肾宣肺方治疗肾阳虚咳嗽变异性哮喘临床研究
引用本文:唐百冬,何军锋.补肾宣肺方治疗肾阳虚咳嗽变异性哮喘临床研究[J].中国中医药信息杂志,2009,16(3):12-13.
作者姓名:唐百冬  何军锋
作者单位:1. 湖南省交通医院,湖南,长沙,410011
2. 湖南中医药大学,湖南,长沙,410007
摘    要:目的观察补肾宣肺方联用西药治疗肾阳虚咳嗽变异性哮喘(CVA)的疗效。方法80例CVA患者随机分为对照组和治疗组,每组40例。对照组口服氨茶碱缓释片0.1~0.2g,2次/d;酮体芬片1mg,1次/d。治疗组在对照组基础上予补肾宣肺方口服。2组均以4周为1个疗程,在第5周评价疗效。结果治疗后2组CD8^+细胞显著升高,CD4^+ 细胞、IgE水平则显著降低,且治疗组与对照组差异有统计学意义(P〈0.05或P〈0.01);治疗组总有效率为87.5%,显著高于对照组的70.0%(P〈0.05);治疗组临床控制患者咳嗽平均缓解天数为(11.5±4.8)d,与对照组(19.3±5.2)d比较,差异亦有统计学意义(P〈0.05)。结论补肾宣肺方联用西药治疗肾阳虚CVA疗程较短,且能改善机体免疫功能。

关 键 词:咳嗽变异性哮喘  补肾宣肺方  CD4+  CD8+  IgE

Clinical Study of Cough Variant Asthma with Kidney Yang Deficiency Treated by Nourishing-kidney and Ventilating-lung Combined with Western Medicine
TANG Bai-dong,HE Jun-feng.Clinical Study of Cough Variant Asthma with Kidney Yang Deficiency Treated by Nourishing-kidney and Ventilating-lung Combined with Western Medicine[J].Chinese Journal of Information on Traditional Chinese Medicine,2009,16(3):12-13.
Authors:TANG Bai-dong  HE Jun-feng
Institution:TANG Bai-dong, HE Jun-feng (1.Hunan Traffic Hospital Changsha 410011, China; 2.Hunan University ofTCM, Changsha 410007, China)
Abstract:Objective To observe the effect of applying nourishing kidney and ventilating lung combined with westem medicine in treating cough variant asthma (CVA) patients with kidney yang deficiency. Method Eighty CVA patients with kidney yang deficiency were divided into contrast group and therapeutic group, each group with 40 patients. The patients in contrast group were treated with AminophyUine sustained-release tablet, 0.1-0.2 g, 2 times a day, as well as Ketotifen tablet, 1 rag, 1 time a day, p.o. As for the therapeutic group, the patients were treated with Chinese herbs of nourishing kidney and ventilating lung based on the treatment of contrast group. One course was 4 weeks for the two groups, and the evaluation were carried out in the fifth week. Results After the treatment, CD8^+ ascended significantly, and CD4^+ and IgE descended significantly compared with the pre-treatment. There were significant differences between two groups (P〈0.05 or P〈0.01). The total effective rate and the mean alleviative period for cough were 87.5% and (11.5 ± 4.8) days respectively in therapeutic group, while those were 70.0% and (19.3±5.2) days respectively in contrast group (P〈0.05). Conclusion Applying Chinese herbs of nourishing kidney and ventilating lung combined with western medicine in treating CVA with kidney yang deficiency could alleviate the cough symptom, shorten treatment period and improve the immunology function significantly.
Keywords:CD4  CD8  IgE
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