针刺治疗焦虑症疗效Meta分析

目的对针刺干扰因素与非针刺干扰因素在焦虑症治疗中的疗效差异进行评价。方法应用Meta分析(meta-analysis)方法对纳入的文献进行同质性检验及合并效应量的检验。结果针刺组与非针刺组疗效数据比较Q=4.316308823,自由度v=5,χ2=11.07(P>0.05),具同质性,因此采用固定效应模型进行分析。计算其合并的ORP=1.759419579,95%CI(1.312894,2.570797),即针刺组与非针刺组相比较有差异。同时针刺对汗密顿焦虑量表(HAMA)影响的评价表明,针刺组与非针刺组相比未见差异。结论针刺治疗焦虑症与目前常用药物相比有优越性,且无严重不良反应,但仍需更多的随机对照试验进行证实。

Meta Analysis on the Effect of Acupuncture Treatment on Anxiety

Objective To assess the effectiveness of the acupuncture treatmeat on anxiety compared with non-acupuncture intervention. Method All of the randomized or quasi-randomized trials involving were reviewed systemantically with the Meta analysis method. The homogeneity test was mode, the standandised mean difference (95% CI) and add risk (OR, 95% CI) were tested. Results Homogeneity test was made among the trials and no significant difference between the acupucture and non-acupuncture groups. Fixed effect model was used. ORP =1.759 419 579, 95% CI (1.336 391, 2.316 356), there was significant difference between the acupuncture group and medicine group as the interventions used to treat anxiety while there was no difference between the two group on the influence in HAMA. Conclusion The Meta analysis results was a trend in favor of acupuncture effectiveness. It seems no serious adverse reactions have been found. But there was no sufficient reliable evidence due to the low quality of the trials and possible publication bias. Further randomized, double blind controlled trials are needed.