檵木叶的化学成分研究

目的研究檵木叶的化学成分。方法药材采用丙酮提取,利用大孔树脂柱、ODS反相柱、硅胶柱、Sephadex LH-20等色谱技术进行提取分离,根据波谱数据对化合物进行结构鉴定。结果从檵木叶中分离得到11个化合物,分别鉴定为β-Dglucopranosyl(Z)-3-hexenol(1)、ampelopsisionoside(2)、红景天苷(3)、2-hydroxy-5-3-hydroxybutyl]phenyl-β-D-glucopyranoside(4)、杨梅素-3-O-α-L-鼠李糖苷(5)、6″-O-galloylsalidroside(6)、绿原酸甲酯(7)、绿原酸(8)、杨梅素-3-O-β-D-葡萄糖苷(9)、alangionoside-A(10)、benzyl-α-L-rhamonopyranosyl-(1→6)-β-D-glucopyranoside(11)。结论化合物1~4、6、10、11为首次从该属植物中分离得到。

Chemical Constituents from Leaves of Loropetalum chinense

OBJECTIVE To study the chemical constituents of Loropetalum chinense leaves. METHODS The acetone extract was isolated and purified by macroporous resin, ODS column, silica gel column and Sephadex LH-20 chromatography. All compounds were identified on the basis of spectral analysis. RESULTS Eleven compounds were isolated from Loropetalum chinense leaves and identified as β-D-glucopranosyl(Z)-3-hexenol(1), ampelopsisionoside(2), salidroside(3), 2-hydroxy-5-phenyl-β-D-glucopyranoside(4), myricetin 3-O-α-L-rhamnoside(5), 6″-O-galloylsalidroside(6), methyl chlorogenate(7), chlorogenic acid(8), myricetin-3-O-β-D-glucoside(9), alangionoside-A(10), and benzyl-α-L-rhamonopyranosyl-(1→6)-β-D-glucopyranoside(11). CONCLUSION Compounds 1-4, 6, 10 and 11 are isolated from this genus for the first time.