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| 引用本文： | ????????????????????л????????????????????壬?????????????.????????????о?[J].中国药学杂志,2016,51(14):1179-1182. |
| 作者姓名： | ????????????????????л????????????????????壬????????????? |
| 作者单位： | 1. ???????????????? 330006?? 2. ??????????Ч???????????豸???????????????? 330006?? 3. ??????????????? ??? 330006?? 4. ?????????????????? 410013 |
| 摘 要： | |
| 关 键 词： | ????? nantenine oxonantenine ???????? ?????? |
Chemical Constituents from the Fruits of Embelia laeta |
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| YANG Lin-jun,HE Ming-zhen,HUANG Wen-ping,XIE Yan-yun,WANG Qi,LI Yan,LI Zhi-feng,FENG Yu-lin,YANG Shi-lin.Chemical Constituents from the Fruits of Embelia laeta[J].Chinese Pharmaceutical Journal,2016,51(14):1179-1182. | |
| Authors: | YANG Lin-jun HE Ming-zhen HUANG Wen-ping XIE Yan-yun WANG Qi LI Yan LI Zhi-feng FENG Yu-lin YANG Shi-lin |
| Institution: | 1.Jiangxi University of Traditional Chinese Medicine, Nangchang 330006, China; 2. State Key Laboratory of Innovative Drug and Efficient Energy-Saving Pharmaceutical Equipment, Nangchang 330006, China; 3.Jiangxi Science & Technology Normal University, Nangchang 330006, China; 4.The Medical College of Hunan Normal University, Changsha 410013, China |
| Abstract: | ??OBJECTIVE To study the chemical constituents of the fruits of Embelia laeta. METHODS The compounds were isolated and purified by MCI,medium pressure TLC on silica gel column, ODS column chromatography, semi-preparative HPLC, and so on. The structures were elucidated on the basis of various modern spectroscopic techniques using physical, chemical properties and spectral data. RESULTS Fifteen compounds were isolated and identified as nantenine(1), oxonantenine(2), physcion(3), syringic acid(4), vanillic acid(5), stigmast-4-ene-3,6-dione(6),(+)-lyoniresinol(7), 7S,8S-threo-4,7,9,9??-tetrahydroxy-3,3??-dimethoxy-8-O-4??-neolignan(8), 1,3-dihydroxylpropyl-(9Z,12Z)-octadeca-9,12-dienate(9),(22E)-5a,8a-epidioxyergosta-6,22-dien-3b-ol(10), dihydroxyisoechinulin A(11), hydroxybenzoic acid(12), stigmasterol(13), sitosterol(14), and daucosterol(15). CONCLUSION Compounds 1, 2, and 5-13 are isolated from the genus Embelia for the first time, and compounds 1-15 are isolated from this plant for the first time. |
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