| 翠云草中双黄酮类成分研究 |
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| 引用本文： | 范晓磊,徐嘉成,林幸华,陈科力. 翠云草中双黄酮类成分研究[J]. 中国药学杂志, 2009, 44(1): 15-19 |
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| 作者姓名： | 范晓磊 徐嘉成 林幸华 陈科力 |
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| 作者单位： | 1.武汉市药品检验所 武汉 430012;2.上虞市盛泰生物化工有限公司 上虞 312369;3.湖北中医学院,湖北省教育部共建中药资源和中药复方重点实验室 武汉 430065 |
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| 基金项目： | 国家自然科学基金资助项目(30470193) |
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| 摘 要： | 目的研究翠云草中的双黄酮类成分。方法利用Sephadex LH-20、硅胶等色谱技术进行分离纯化,用UV,IR,NMR,MS等方法确定结构。结果分离得到5个双黄酮化合物,分别鉴定为穗花杉双黄酮(Amentoflavone,Ⅰ)、罗波斯塔双黄酮(Robustaflav-dimethyl ether,Ⅲ)、2″,3″-二氢-4′-甲氧基穗花杉双黄酮(2″,3″-dihydro-4′-O-methyl Amentoflavone,Ⅳ)、7″-甲氧基-2,3,2″,3″-四氢扁柏双黄酮(7″-O-methyl-2,3,2″,3″-tetrahydrohinokiflavone,Ⅴ)。结论化合物Ⅱ,Ⅲ为首次从该植物中分离得到,化合物Ⅳ,Ⅴ为新化合物。
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| 关 键 词： | 翠云草 罗波斯塔双黄酮 罗波斯塔-4′-甲醚 2″ 3″-二氢-4′-甲氧基穗花杉双黄酮 7″-甲氧基-2 3 2″ 3″-四氢扁柏双黄酮 |
| 收稿时间： | 2008-01-04; |
Study on Biflavonoids from Selaginella uncinata(Desv.) Spring |
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| FAN Xiao-lei,,XU Jia-cheng,LIN Xing-hua,CHEN Ke-li. Study on Biflavonoids from Selaginella uncinata(Desv.) Spring[J]. Chinese Pharmaceutical Journal, 2009, 44(1): 15-19 |
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| Authors: | FAN Xiao-lei XU Jia-cheng LIN Xing-hua CHEN Ke-li |
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| Affiliation: | 1.Wuhan Institute for Drug Control,Wuhan 430012,China;2 Shangyu Shengtai Biochemistry Ltd.,Shangyu 312369 China;3.Hubei College of Traditional Chinese Medicine,Key Laboratory of TCM Resource and TCM Compound Co-constructed by Hubei Province and Ministry of Education,Wuhan 430065,China |
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| Abstract: | OBJECTIVE To study the biflavonoids of Selaginella uncinata(Desv.) Spring.METHODS The biflavonoids were isolated and purified by column chromatography on silica gel column and Sephadex LH-20 column.Their structure were determined by spectroscopic methods including UV,IR,NMR and MS.RESULTS Five biflavonoids including amentoflavone,robustaflavone,robustaflavone-4′-dimethyl ether,2″,3″-dihydro-4′-O-methylamentoflavone,7″-O-methyl-2,3,2,3′-tetrahydrohinokiflavone were isolated from S.uncinata(Desv.) Spring.CONCLUSION Compound Ⅱ,Ⅲ are firstly found in this plant.Compound Ⅳ,Ⅴ are new compounds. |
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| Keywords: | S.uncinata')" href=" #" >S.uncinata robustaflavone robustaflavone-4′-dimethyl ether 2″ O-methylamentoflavone')" href=" #" > 3″-dihydro-4′-O-methylamentoflavone O-methyl-2')" href=" #" > 7″-O-methyl-2 3 2″ 3″-tetrahydrohinokiflavone |
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