| 川楝子的化学成分研究 |
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| 引用本文： | 谢帆,张勉,张朝凤,王峥涛,余伯阳.川楝子的化学成分研究[J].中国药学杂志,2008,43(14):1066-1069. |
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| 作者姓名： | 谢帆 张勉 张朝凤 王峥涛 余伯阳 |
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| 作者单位： | 中国药科大学,a现代中药教育部重点实验室 ;b生药学研究室,南京 210038 |
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| 摘 要： | 目的研究川楝子的化学成分。方法采用硅胶、凝胶柱色谱等方法对川楝子的化学成分进行分离,运用波谱分析技术和理化常数对照等方法对化合物结构进行鉴定。结果分离鉴定了16个化合物,分别鉴定为表松脂醇(1),clema-phenol A(2),medioresinol(3),(±)balanophonin(4),evofolin-B(5),槲皮素(6),异槲皮苷(7),芦丁(8),阿魏酸(9),对羟基苯甲醛(10),松柏醛(11),丁香酸(12),异香草酸(13),对羟基苯甲酸(14),5-羟甲基糠醛(15)和cirsiumaldehyde(16)。结论化合物6为首次从川楝子中分离得到,其余化合物均为首次从楝属植物中分离得到。
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| 关 键 词： | 川楝子 化学成分 木脂素 黄酮 酚酸 |
| 收稿时间： | 2007-06-22; |
Studies on Chemical Constituents in Fruit of Melia toosendan |
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| XIE Fana,b,ZHANG miana,b,ZHANG Chao-fenga,b,WANG Zheng-taoa,b,YU Bo-yanga.Studies on Chemical Constituents in Fruit of Melia toosendan[J].Chinese Pharmaceutical Journal,2008,43(14):1066-1069. |
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| Authors: | XIE Fana b ZHANG miana b ZHANG Chao-fenga b WANG Zheng-taoa b YU Bo-yanga |
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| Institution: | a. Key Laboratory of Modern Chinese Medicines of Ministry of Education;b.Department of Pharmacognosy,China Pharmaceutical University,Nanjing 210038,China |
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| Abstract: | OBJECTIVE To investigate the chemical constituents of Melia toosendan.METHODS The chemical constituents were isolated by various column chromatographic methods and structurally elucidated by spectral evidences.RESULTS Sixteen compounds were obtained and identified as epipinoresinol(1),clemaphenol A(2),medioresinol(3),(±)balanophonin(4),evofolin- B(5),quercetin(6),isoquercitrin(7),rutin(8),ferulic acid(9),p-hydroxybenzaldehyde(10),coniferylaldehyde(11),syringic acid (12),isovanillic acid(13),p-hydroxybenzoic acid(14),5-hydroxymethyl-fuffural(15)and cirsiumaldehyde(16).CONCLUSION Compound 6 was firstly isolated from this plant while other compounds were isolated from this genus for the first time. |
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| Keywords: | Melia toosendan" target="_blank">Melia toosendan')" href="#">Melia toosendan chemical constituents lignans flavonoids phenolic compounds |
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