藏木香的化学成分研究

 目的 研究菊科旋覆花属植物藏木香的化学成分。 方法 利用硅胶柱色谱、Sephadex LH-20和反相RP-18柱色谱等手段进行分离纯化，并通过波谱数据鉴定结构。 结果 分离鉴定了13个化合物：deactyl-γ-cycloepitulipinolide (1)，5-deoxy-5-hydroperoxytelekin (2)，11，13-dihydroisoalantolactone (3)，8-epi-ivangustin (4)，alloalantolactone (5)，clemaphnol A (6)，dammara-20，24-dien-3β-OAc(7)，木栓酮(Friedelin，8)，反式咖啡酸乙酯 (ethyl trans-3，4-dihydroxycinnamate， 9)，丁香酸(syringic acid， 10)，5-羟甲基糠醛(5-hydroxymethyl-furaldehyde， 11)，正丁基-β-D-吡喃果糖苷 (n-Butyl-β-D-fructopyranoside， 12)，乙基-β-D-吡喃果糖苷 (ethyl-β-D-fructopyranoside，13)。结论 化合物1，2，6~13为首次从该属植物中分离，化合物3，4为首次从该植物中分离。

Study on Chemical Constituents in Roots of Inula racemosa

OBJECTIVE To investigate the chemical constituents in the roots of Inula racemosa. METHODS The isolation and purification were performed by various chromatographies such as silica gel， Sephadex LH-20 and RP-C₁₈ column chromatography and so on. RESULTS Thirteen compounds were isolated and identified asdeactyl-γ-cycloepitulipinolide (1)，5-deoxy-5-hydroperoxytelekin (2)，11，13-dihydroisoalantolactone (3)，8-epi-ivangustin (4)， alloalantolactone (5)， clemaphnol A (6)， dammara-20，24-dien-3β-OAc (7)， friedelin (8)， ethyl trans-3，4-dihydroxycinnamate (9)， syringic acid (10)，5-hydroxymethyl-furaldehyde (11)，n-butyl-β-D-fructopyranoside (12)， ethyl-β-D-fructopyranoside (13).CONCLUSION Compounds 1， 2， 6-13 are isolated from the genus of Inula for the first time， and compounds 3 and 4 are isolated from this plant for the first time.