| 清眩丸质量标准初探 |
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| 引用本文： | 谷学新,毛彦杰,岳敏,范国强,段豫萍,秦晨.清眩丸质量标准初探[J].中国药学杂志,2004,39(10):786-787. |
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| 作者姓名： | 谷学新 毛彦杰 岳敏 范国强 段豫萍 秦晨 |
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| 作者单位： | 1. 首都师范大学化学系,北京,100037
2. 北京同仁堂股份有限公司科学研究所,北京,100011 |
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| 摘 要： | 目的 建立清眩丸的质量标准。方法 采用TLC对处方中白芷、川芎进行定性鉴别;用HPLC测定欧前胡素的含量。结果 在TLC中均能检出白芷、川芎;欧前胡素在0.018 2～0.091 0μg·mL-1内具有良好的线性关系,r=0.999 9,平均回收率为99.52％,RSD=2.37％(n=5)。结论 所建立的方法简便、准确、可靠,可作为控制该药品的质量标准,本品每丸含白芷以欧前胡素计,不得少于0.3 mg。
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| 关 键 词： | 清眩丸 欧前胡素 质量标准 |
| 文章编号： | 1001-2494(2004)10-0786-02 |
| 收稿时间： | 2003-12-10; |
Studies on quality standard of Qingxuan pills |
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| GU Xue-xin,MAO Yan-jie,YUE Min,FAN Guo-qiang,DUAN Yu-ping,QIN Chen.Studies on quality standard of Qingxuan pills[J].Chinese Pharmaceutical Journal,2004,39(10):786-787. |
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| Authors: | GU Xue-xin MAO Yan-jie YUE Min FAN Guo-qiang DUAN Yu-ping QIN Chen |
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| Institution: | 1.Department of Chemistry,Capital Normal University,Beijing 100037,China;2.Scientific Research Institute of Beijing Tong Ren Tang Co.Ltd,Beijing 100011,China |
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| Abstract: | OBJECTIVE To establish the quality standard of Qingxuan pills.METHODS Radix Angelicae Dahuricae and Rhizoma Chuanxiong were determined by TLC. The content of imperatorin was detennined by HPLC. RESULTS Radix Angelicas Dahuricae and Rhizoma Chuanxiong were checked out by TLC.The linear range of imperatorin was 0.018 2～0.091 0μg·mL-1 with a good correlation coeffe-cient(r=0.999 9).The recovery was 99.52%,and RSD was 2.37 %(n=5). CONCLUSION The method is simple, accurate and credi-bile. The method was acceptable as the quality control standard of Qingxuan pills. |
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| Keywords: | Qingxuan pills imperatorin quality control |
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