Antifungal activity of benzoic acid derivatives from Piper lanceaefolium. |
| |
| Authors: | Andrés López Dong Sheng Ming G H Neil Towers |
| |
| Institution: | Department of Botany, University of British Columbia, #3529-6270 University Boulevard, Vancouver, B.C., Canada V6T 1Z4. |
| |
| Abstract: | Bioactivity-guided fractionation of a methanol extract from the leaves of Piper lanceaefolium resulted in the isolation of four new benzoic acid derivatives (1-4), together with taboganic acid, pinocembrin, and pinocembrin chalcone. Lanceaefolic acid methyl ester (3) and pinocembrin chalcone displayed activity against Candida albicans with a minimal inhibitory concentration value of 100 microg/mL in both cases. |
| |
| Keywords: | |
|
|
