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Sesquiterpene lactones from Lychnophora ericoides
Authors:Sakamoto Humberto T  Flausino Douglas  Castellano Eduardo E  Stark Christian B W  Gates Paul J  Lopes Norberto P
Institution:Faculdade de Filosofia Ciências e Letras de Ribeir?o Preto, Universidade de S?o Paulo, CEP 14.040-903, Brazil.
Abstract:Two new sesquiterpene lactones, (4S,6R,7S,8S,10R,11S,16R)-1-oxo-3(10),8(16)-diepoxy-16-methylprop-1Z-enyl-16-methoxygermacra-2-en-6(12)-olide (1) and (4S,6R,7S,8S,10R,11S)-1-oxo-3,10-epoxy-8-angeloyloxygermacra-2-en-6(12)-olide (2), were isolated from Lychnophora ericoides. Their structures, including absolute configuration, were established by spectroscopic methods, including single-crystal X-ray analysis. Monitoring the furanoheliangolide metabolism of L. ericoides revealed an increase in biosynthesis during the plant flowering period.
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