Oceanapiside, an antifungal bis-alpha,omega-amino alcohol glycoside from the marine sponge Oceanapia phillipensis |
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| Authors: | Nicholas G M Hong T W Molinski T F Lerch M L Cancilla M T Lebrilla C B |
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| Institution: | Department of Chemistry, University of California, Davis 95616, USA. |
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| Abstract: | The structure of oceanapiside, an antifungal alpha, omega-bis-aminohydroxylipid glycoside from the temperate marine sponge Oceanapia sp., was elucidated by a combination of 2D NMR, chemical degradation/correlation, and MALDI MS-MS spectrometry. Oceanapiside exhibits antifungal activity against Candida glabrata at 10 micrograms/mL (MIC). |
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