| 丹参对糖尿病性视网膜病变患者脂质过氧化物及超氧化物歧化酶的影响 |
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| 引用本文： | 柯晓云,吴艺.丹参对糖尿病性视网膜病变患者脂质过氧化物及超氧化物歧化酶的影响[J].中国中医眼科杂志,1997(4). |
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| 作者姓名： | 柯晓云 吴艺 |
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| 作者单位： | 第一军医大学附属珠江医院眼科 |
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| 摘 要： | 目的观察丹参对糖尿病性视网膜病变患者血浆脂质过氧化物（ｌｉｐｉｄｐｅｒｏｘｉｄｓ，ＬＰＯ）含量和红细胞超氧化物歧化酶（ｓｕｐｅｒｏｘｉｄｅｄｉｓｍｕｔａｓｅ，ＳＯＤ）活性的影响。方法：应用丹参对３７例糖尿病性视网膜病变患者进行治疗，测定治疗前后患者血浆ＬＰＯ含量及红细胞ＳＯＤ活性。３５例健康人作对照。结果：糖尿病性视网膜病变患者血浆ＬＰＯ含量明显高于健康人（Ｐ＜００１），红细胞ＳＯＤ活性明显低于健康人（Ｐ＜００１）。用丹参治疗后患者血浆ＬＯＰ含量明显降低（Ｐ＜００１），红细胞ＳＯＤ活性明显升高（Ｐ＜００１）。结论：丹参能有效地降低糖尿病性视网膜病变患者血浆ＬＰＯ含量，升高红细胞ＳＯＤ活性。
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| 关 键 词： | 丹参 糖尿病性视网膜病变 脂质过氧化物 超氧化物歧化酶 |
Effect of Salvia mitiorrhiza on lipidperoxide and superoxide dismutase of the patients with diabetic retinopathy |
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| Ke Xiaoyun,Wu Yi.Effect of Salvia mitiorrhiza on lipidperoxide and superoxide dismutase of the patients with diabetic retinopathy[J].Journal of Traditional Chinese Ophthalmology,1997(4). |
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| Authors: | Ke Xiaoyun Wu Yi |
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| Institution: | Ke Xiaoyun,Wu Yi Department of Ophthalmology,Affliated ZhuJiang Hospital,the First Military Medical University,Guangzhou,510282 |
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| Abstract: | s OBJECTIVE: To observe the effect of Salvia miltiorrhiza on lipidperoxide (LPO) and superoxide dismutase(SOD) of the patients with diabetic retinopathy (DR) METHODS: Thirty-seven patients with DR were treated with Salvia miltiorrhiza and the level of plasma LPO and the activity of erythrocyte SOD were measured before and after the treatment Thirty-five heathy persons were used as a control group RESULTS: The plasma LPO level in the patients with DR was much higher than in the control group( P <0 01) and the erythrocyte SOD activity was significantly lower than the control group( P <0 01) before treatment After treatment with salvia miltiorrhiza, the LPO level was decreased and the SOD activity was increased significantly in the patients with RD( P <0 01) CONCLUSIONS: Salvia miltiorrhiza can decrease the plasma LPO level and increase the erythrocyte SOD activity in patient with DR |
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| Keywords: | Salvia miltiorrhiza diabetic retinopathy lipidperoxide superoxide dismutase |
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