中药贴敷及口服治疗干眼的疗效观察

目的探讨中药贴敷及口服治疗干眼的疗效。方法将门诊就诊的干眼患者130例（260只眼），随机分为治疗组65例（130只眼），其中男25例（50只眼），女40例（80只眼），年龄25～60岁；病程10天～1年。对照组65例，其中男20例（40只眼），女45例（90只眼），年龄25—60岁；病程10天～1年。两组基线资料比较差异无统计学意义（P〉0．05），具有可比性。两组均给予玻璃酸钠滴眼液局部点眼；治疗组在此基础上进行中医辨证论治及中药冰片贴敷治疗。共分为三型：肺阴不足型，脾胃湿热型，肝肾阴虚型，分别给予中药口服。观察治疗前后患者的干眼症状积分，泪膜破裂时间，泪液分泌试验。结果治疗组65例（130只眼），总有效率93．8％；对照组65例（130只眼），总有效率84．6％；治疗组疗效优于对照组（P〈0．05）。结论在常规治疗基础上结合中医辨证论治，能显著改善干眼患者的泪液分泌，抑制泪液蒸发，稳定泪膜。

Clinical observation on dry eye treatment by application of Chinese medicine to acupoint and oral medication

OBJECTIVE To study the effect of curing dry eye by applying Chinese medicine to acupoint and oral medication. METHODS One hundred and thirty dry eye patients were randomly divided into treatment group and reference group. Each group, whose age was from 25 to 60 years old, had 25 males and 40 females with history from 10 days to 1 year. Data of two groups were comparable due to no significant difference （P〉0.05）. The two groups were both given sodium hyaluronate topically, and treatment group further got TCM differentiation treatment and Chinese medicine borneol acupoint therapy. Three kinds of patients, lung yin deficiency, spleen stomach damp heat syndrome, and yin deficiency of liver and kidney, were treated by oral medication. Compared with dry eye symptoms, tear break-up time, Schirmer test before and after treatment. It was obvious that treatment group had 93.8% efficiency and a better effect than reference group with 84.6% （P〈0.05）. CONCLUSIONS Conventional therapy combined with TCM differentiation could considerably improve the tear secretion of dry eye patients, inhabit tear evaporation and stabilize the film.