非动脉炎性前部缺血性视神经病变24h动态血压的初步分析

目的 初步分析非动脉炎性前部缺血性视神经病变(non-arteritic anterior ischaemic optic neuropathy,NAION)患者的24h动态血压(ambulatory blood pressure monitoring,ABPM)特点.方法 选取NAION患者19例作为病例组,同期健康体检者19例作为正常对照组,分别记录其24h的收缩压、舒张压和平均动脉压,描绘其动态曲线并分类,分析血压晨峰情况.结果 19例NAION患者日间收缩压低于正常对照组(P＜0.01),昼夜的舒张压均高于正常组(P＜0.01)；血压变化曲线中有7例为非勺型,其余均为反勺型；血压晨峰(morning blood pressure surge,MBPS)值＞35mmHg者3例,≥10mmHg～＜35mmHg者11例,≥0mmHg～＜10mmHg者2例,＜0mmHg者3例.结论 NAION患者的日间低收缩压、昼夜高舒张压、反勺型和非勺型血压曲线、低血压晨峰均可能为靶器官损害的危险因素,需进一步研究.

Preliminary analysis on 24-hour ambulatory blood pressure monitoring of 19 patients with non-arteritic anterior ischemic optic neuropathy

OBJECTIVE To conduct the preliminary analysis of the characteristics of 24-hour ambulatory blood pressure monitoring(ABPM) of the 19 patients with non-arteritic anterior ischemic optic neuropathy(NAION).METHODS Chose 19 cases of NAION group and normal control group respectively,and recorded its 24-hour systolic,diastolic and mean arterial pressure,then portrayed the curve and analyzed the morning blood pressure surge(MBPS).RESULTS The daytime systolic blood pressure of 19 cases with NAION was lower than the normal group(P<0.01);The diastolic blood pressure of the day and the night was higher than the normal group(P<0.01);The blood pressure curves concluded seven non-dippers and eleven reverse-dippers.MBPS values were measured(MBPS≥35 mmHg,3cases;10 mmHg ≤MBPS<35 mmHg,11cases;0≤MBPS<10 mmHg,2cases,MBPS<0,3cases).CONCLUSIONS NAION patients with low systolic blood pressure in the daytime,high diastolic blood pressure in the day and the night,reverse-dippers and non-dippers of the blood pressure curve,low morning blood pressure surge were all the possible risk factors damaging target organ,and further researches are needed.