肝病瘀血舌象不同证型血液流变学的临床实验研究

目的:探讨肝病瘀血舌象患者的血液生化物质的变化与不同血瘀证型是否内在联系。方法:用常规方法分别进行血液流变学的各项指标检测。结果:肝病瘀血舌患者不同证型组湿热瘀滞组、肝瘀痰阻组、气滞血瘀组、气虚血瘀组的血液流变学指标与正常组比较有显著差异;肝病瘀血舌患者不同证型组与气虚血瘀组比较,湿热瘀滞组、肝瘀痰阻组、气滞血瘀组的全血高切黏度、血浆黏度、红细胞压积高于气虚血瘀组(P<0.05或P<0.01)。结论:肝病瘀血舌不同血瘀证型有其不同的中医生理病理基础,肝病瘀血舌血液流变性与中医不同血瘀证型密切相关。

Clinical empirical observation of hemorheology about hepatopathy with tongue of blood stasis of different syndromes

Objective: To explore the pathology mechanism of hepatopathy tongue of blood stasis(TBS)on molecule level.Methods: Tongue of blood stasis of hepatopathy TBS and blood stasis syndrome and mechanism of their formation were probed by means of the test of molecular and prospective study.Results: Hemorheology of the hepatopathy blood stasis syndrome(BSS) group was differentiated significantly from normal group,such as dampness and heat and blood stasis syndrome(DHBSS) group and phlegm and blood stasis syndrome(PBSS) group as well as qi and blood stasis syndrome group(QBSS)(P<0.05 or P<0.01).Hepatopathy BSS group was compared with Qi deficiency and blood stasis syndrome(QDBSS) group in hemorheology plasma viscosity and hematocrit and whole blood viscosity of all the hepatopathy BSS group were risen significantly compared with QDBSS,such as DHBSS,PBSS,QBSS(P<0.01).Conclusions: The experiment verify the result that characterized by or possessing qualities generally attributed to tongue of blood stasis of different syndromes based on different biochemical substance and physics and chemistry and pathology.Experiments showed that transformation of biochemical substance of tongue of blood stasis is closely allied to BSS.Its findings provide the scientific foundation for syndrome differentiation and clinic appliance of the medicine with promoting blood circulation to remove blood stasis.