消痞通降汤治疗功能性消化不良的临床观察

目的:观察中药消痞通降汤治疗寒热错杂型功能性消化不良的疗效。方法:采用随机、对照的观察方法,将120例患者分为对照组和治疗组,治疗组采用消痞通降汤,对照组采用吗丁啉治疗。经过4周治疗,采用临床症状积分法,观察功能性消化不良的上腹饱胀、早饱、嗳气、上腹疼痛等症状缓解情况。结果:经过治疗后,中药消痞通降汤可以明显改善上腹饱胀、早饱、嗳气、上腹疼痛、恶心、厌食、烧心、泛酸症状(P<0.01),尤其是早饱感、上腹痛、烧心、泛酸、嗳气的改善效果非常显著,疗效优于对照组(P<0.05),其总疗效也明显优于对照组(P<0.05)。结论:以辛开苦降法为组方原则的消痞通降汤对FD的临床症状评分和治疗的总有效率均明显高于吗丁啉对照组,有一定的疗效。

Clinical Observation of Functional Dyspepsia Treated by Xiaopi Tongjiang Decoction

Objective:To explore the effect of Xiaopi Tongjiang Decoction on the treatment of Functional Dyspepsia.Methods:120 patients with functional dyspepsia were randomly divided into the experimental group(n=60)and the control group(n=60).The experimental group was given Xiaopi Tongjiang Decoction,and the control group was only given Domperidone for 4 weeks.The improvement of clinical symptoms such as stomach burn,abdominal distention,upper abdominal pain and eructation were evaluated by clinical symptom score.Results:After 4 weeks’ treatment,the abdominal symptom scores of both groups were significantly lower than those before the treatment(P<0.05),and the improvement of abdominal symptom score of control group was significantly lower than that of experimental group(P<0.05).Conclusion:Xiaopi Tongjiang Decoction is more effective in patients with functional dyspepsia than Domperidone.It deserves clinical expansion.