| 中风急性期证候与血清CRP的相关性及ROC曲线分析 |
| |
| 引用本文： | 章正祥,;宣江雷,;刘海顺,;黄春华,;查青林,;饶旺福,;曹克刚,;李涛,;范吉平.中风急性期证候与血清CRP的相关性及ROC曲线分析[J].辽宁中医杂志,2009(11):1830-1832. |
| |
| 作者姓名： | 章正祥 ;宣江雷 ;刘海顺 ;黄春华 ;查青林 ;饶旺福 ;曹克刚 ;李涛 ;范吉平 |
| |
| 作者单位： | [1]浙江省中医院神经内科,浙江杭州310006; [2]江西中医学院研究生部,江西南昌330004; [3]江西中医学院附属医院神经内科,江西南昌330006; [4]江西省南昌市中西医结合医院神经内科,江西南昌330003; [5]《江西中医药》编辑部,江西南昌330006; [6]北京中医药大学东直门医院神经内科,北京100700; [7]中国中医科学院,北京100700 |
| |
| 摘 要： | 目的:探讨中风急性期证候与CRP的相关性及其对临床的应用价值。方法:运用散射比浊法测定50例中风急性期(均在发病2周内入院)患者血清C反应蛋白(CRP),并进行受试者工作特征曲线(ROC)分析。结果:中风急性期患者CRP水平与痰证积分有一定的相关性(P<0.05),与证候程度无明显相关性(P>0.05);痰证积分对血清CRP阳性诊断的ROC曲线下面积为0.700(SE:0.076;95%CI:0.550～0.849),其诊断界点为10.5分。结论:痰证积分可以预测中风急性期CRP阳性,有利于卒中的临床治疗,扩大《中风病辨证诊断标准(试行)》(1994)的临床使用范围。
|
| 关 键 词： | 中风 痰证 预后 C反应蛋白 ROC曲线 |
Analysis of Correlation and Receiver Operating Characteristic Curve on Stroke Acute Stage Syndrome and Serum C -reactive Protein |
| |
| Institution: | ZHANG Zheng-xiang,XUAN Jiang-lei ,LIU Hai-shun ,HUANG Chun-hua, ZHA Qin-lin, RAO Wang-fu,CAO Ke-gang,LI Tao,FAN Ji-ping( 1. Department of Neurology, Zhejiang Provincial Hospital of Traditional Chinese Medicine ,Hangzhou 310006 ,Zhejiang, China; 2. Department of Postgraduate ,Jiangxi University of Traditional Chinese Medicine ,Nanchang 330004 ,Jiangxi, China; 3. Department of Neurology,Jiangxi University of Traditional Chinese Medicine Affiliated Hospital ,Nanchang 330006 ,Jiangxi, China; 4. Department of Neurology,Nanehang combination of TCM with Western medicine Hospital,Nanchang 330003 ,Jiangxi, China; 5. Jiangxi Chinese Medicine Editorial Depart ment,Jiangxi University of Traditional Chinese Medicine ,Nanchang 330006 ,Jiangxi, China; 6. Department of Neurology,Beijing University of Chinese Medicine Affiliated Dongzhimen Hospital ,Beijing 100700, China ; 7. China Academy of Chinese Medical Sciences ,Beijing 100700, China) |
| |
| Abstract: | Objective：To explore the relation between Chinese medicine acute stage syndromes of stroke and C -reactive Protein （CRP） and its clinical application value. Methods ： Serum CRP of 50 inpatients with acute stage of stroke （ onset within 2 weeks） were tested by nephelometry and was analyzed by ROC. Results：CRP of patients with stroke acute stage and phlegm syndrome accumulated scores had some correlation（ P 〈 0.05 ）, had no significant difference with syndrome extent（ P 〉 0.05 ）. Area Under the ROC curve which Phlegm syndrome accumulated scores predicted the positive CRP was 0. 700 （SE：0.076 ;95% CI： 0. 550 - 0. 849）. Its diagnostic cutoff point was 10. 5 scores. Conclusion：Phlegm syndrome accumulated scores could predict postive CRP of stroke acute stage, and it could be good for the chnical treatment of the stroke. Simultaneously it has broadened the clinical serviceable range of stroke differentiation of syndrome diagnostic criteria（trying） （1994）. |
| |
| Keywords: | stroke phlegm syndrome prognosis C-reactive protein receiver operating characteristic curve |
| 本文献已被 维普 等数据库收录！ |
|
