桑苏饮加味治疗肺切除术后痰潴留疗效观察

目的观察桑苏饮加味治疗肺切除术后痰潴留患者的临床疗效。方法将2018年2月—2019年3月河北省中医院外三科诊治的120例肺切除术后痰潴留患者随机分为对照组和观察组,每组60例。对照组给予呼吸科常规护理、抗感染和化痰治疗,观察组在对照组治疗基础上给予桑苏饮加味治疗。观察2组患者治疗1周后炎症指标白细胞计数(WBC)和超敏C反应蛋白(hs-CRP)]变化,记录2组患者临床疗效、痰液量和痰液性状疗效、抗生素使用时间、胸引管拔管时间、咳痰时间、住院费用及不良反应发生率。结果治疗1周后,2组患者WBC和hs-CRP水平均明显下降(P均<0.05),且观察组均明显低于对照组(P均<0.05);观察组痰液量和痰液性状的总有效率分别为90.0%(54/60)和91.7%(55/60),对照组痰液量和痰液性状的总有效率分别为75.0%(44/60)和76.7%(46/60),观察组和对照组临床总有效率分别为81.7%(49/60)和65.0%(39/60),观察组均明显高于对照组(P均<0.05);观察组抗生素使用时间、胸引管拔管时间、咳痰时间均明显短于对照组(P均<0.05),住院费用明显少于对照组(P<0.05);观察组和对照组不良反应发生率分别为6.7%(4/60)和16.7%(10/60),观察组明显低于对照组(P<0.05)。结论桑苏饮加味治疗肺切除术后痰潴留疗效确切,可有效减轻肺部炎症,缩短恢复时间,减少住院费用。

Observation on curative effect of modified Sangsuyin Decoction on phlegm retention after pulmonary resection

Objective It is to observe the clinical effect of modified Sangsuyin Decoction in the treatment of patients with phlegm retention after pulmonary resection. Methods A total of 120 patients with phlegm retention after pulmonary resection who were diagnosed and treated in Hebei Provincial Hospital of Traditional Chinese Medicine from February 2018 to March 2019 were randomly divided into a control group and an observation group, 60 cases in each group. The control group was given routine nursing care of respiratory department, anti-infection and phlegm-relieving treatment, and the observation group was given modified Sangsu Decoction on the basis of the treatment of the control group. The changes of inflammatory indexes white blood cell count(WBC) and high-sensitivity C-reactive protein(hs-CRP)] of patients in the two groups were observed after one week of treatment, and the clinical efficacy, sputum volume and sputum properties, the duration of antibiotic use, chest catheter extubation time, expectoration time, hospitalization costs and incidence of adverse reactions of the two groups were recorded. Results After 1 week of treatment, the levels of WBC and hs-CRP in the two groups were significantly decreased(P all <0.05), and the levels of the observation group were significantly lower than those of the control group(P all<0.05). The total effective rates of sputum volume and sputum characteristics in the observation group were 90.0%(54/60) and 91.7%(55/60), respectively, and the total effective rates of sputum volume and sputum characteristics in the control group were 75.0%(44/60) and 76.7%(46/60), the total clinical effective rates of the observation group and the control group were 81.7%(49/60) and 65.0%(39/60), respectively, all the rates in the observation group were significantly higher than those in the control group(P all<0.05). The duration of antibiotic use, chest tube extubation time and expectoration time in the observation group were significantly shorter than those in the control group(P all<0.05), and hospitalization costs was significantly lower than those in the control group(P<0.05). The incidence of adverse reactions in the observation group and the control group respectively were 6.7 %(4/60) and 16.7%(10/60), the observation group was significantly lower than the control group(P<0.05). Conclusion Modified Sangsuyin Decoction has a definite curative effect on phlegm retention after pulmonary resection, and can effectively relieve lung inflammation, shortened recovery time, and reduced hospitalization costs.