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半枝莲醇提物抗肿瘤活性的研究
引用本文:王刚,董玫,刘秀书,汤建华.半枝莲醇提物抗肿瘤活性的研究[J].现代中西医结合杂志,2004,13(9):1141-1142.
作者姓名:王刚  董玫  刘秀书  汤建华
作者单位:河北医科大学基础医学院,河北,石家庄,050017
摘    要:目的 研究中药半枝莲醇提物的抗肿瘤活性。方法 采用小鼠腋下接种肿瘤细胞法测定了半枝莲醇提物的抗肿瘤活性 ;采用MTT法测定了半枝莲醇提物对小鼠脾细胞的增殖活性。结果 半枝莲醇提物对移植性肿瘤 (肉瘤S180 和肝癌H2 2 )具有显著的抑制作用 ,而对小鼠脾细胞的增殖具有促进作用 ,并有较好的剂量依赖关系。结论 中药半枝莲有可能通过增强机体的免疫力来实现其抗肿瘤活性

关 键 词:半枝莲醇提物  抗肿瘤活性  脾细胞  免疫力
文章编号:1008-8849(2004)09-1141-02
修稿时间:2003年11月17

Anti-tumor activity study of extract from Scutellaria barbata D. Don
WANG Gang,DONG Mei,LIU Xiu-shu,TANG Jian-hua.Anti-tumor activity study of extract from Scutellaria barbata D. Don[J].Modern Journal of Integrated Chinese Traditional and Western Medicine,2004,13(9):1141-1142.
Authors:WANG Gang  DONG Mei  LIU Xiu-shu  TANG Jian-hua
Abstract:Objective It is to study the ante-tumor activity of the extract from Scutellaria barbata D. Don.Methods The anti-tumor activity of the extract from Scutellaria barbata D. Don was measured with KM mice being injected tumor cells. The multiplication activity of the extract from Scutellaria barbata D. Don on mice spleen cells was measured with MTT.Results The extract from Scutellaria barbata D. Don had obvious suppression effect on transplanted tumor. But it could accelerate the multiplication of mice spleen cells and which had significant dose-dependence relationship.Conclusion The extract from Scutellaria barbata D. Don maybe realize its anti-tumor activity by toning up immunity.
Keywords:extract from Scutellaria barbata D  Don  anti-tumor activity  spleen cell  immunity
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