五苓散加减治疗老年痔疮合并慢性传输型便秘疗效观察

目的观察五苓散加减治疗老年痔疮合并慢性传输型便秘的临床疗效。方法将2017年5月—2019年8月广州中医药大学第一附属医院收治的118例老年痔疮合并慢性传输型便秘(STC)患者纳入本次研究,依据随机数字表将入选患者均分为常规组与研究组,常规组采取常规治疗,研究组在常规治疗的基础上联合应用五苓散加减治疗。治疗3周后,观察2组患者结肠传输功能、便秘症状积分、痔核直径及患者生活质量的变化情况,统计2组患者临床疗效及治疗期间不良反应发生率。结果治疗后,2组患者结肠传输功能试验结果、CSS得分、痔核直径均较本组治疗前降低,且研究组均低于常规组,差异均有统计学意义(P均<0.05);治疗后,2组患者PAC-QOL各维度得分均较本组治疗前降低,且研究组均低于常规组,差异均有统计学意义(P均<0.05);研究组总有效率为91.53%(54/59)、愈显率为64.41%(38/59),常规组依次为77.97%(46/59),47.46%(2/59),研究组临床疗效优于常规组(P均<0.05)。治疗过程中2组均未见明显不良反应发生。结论五苓散加减治疗老年痔疮合并慢性传输型便秘疗效良好,能够有效改善患者结肠传输功能,可在一定范围内缩小痔核预防痔疮进展,从而全面提高患者生活质量。

Observation on the curative effect of modified Wuling Powder on senile hemorrhoids complicated with chronic transit constipation

Objective It is to observe the clinical efficacy of modified Wuling Powder in the treatment of senile hemorrhoids with chronic transit constipation.Methods A total of 118 elderly patients with hemorrhoids and chronic transit constipation(slow transit costipation,STC)admitted to the First Affiliated Hospital of Guangzhou University of Chinese Medicine from May 2017 to August 2019 were selected into this study,and were randomly divided into a routine group and a study group according to the simple random digital table.The routine group was treated with routine therapy,and the study group was treated with modified Wuling Powder based on the routine group.After 3 weeks of treatment,the changes in colonic transit function,constipation symptom score,hemorrhoid diameter,and quality of life of the patients in the two groups were observed,the clinical curative effects were evaluated and the incidence of adverse reactions during the treatment were counted in the two groups.Results After treatment,the results of colonic transit function test,CSS score,and hemorrhoid diameter of the two groups were all decreased compared with those before treatment,and the study group was lower than the routine group,the differences were statistically significant(P<0.05).After treatment,the scores of PAC-QOL dimensions of the two groups were lower than those before treatment,and the study group was lower than the routine group,the differences were statistically significant(P<0.05).The total effective rate of the study group was 91.53%(54/59),the cure rate was 64.41%(38/59),those in the routine group respectively were 77.97%(46/59),47.46%(2/59),the clinical efficacy in the study group was better than that of the conventional group(P<0.05).There was no obvious side effect occurred during the treatment period.Conclusion Wuling Powder has a good effect in the treatment of elderly hemorrhoids complicated with chronic transit constipation.It can effectively improve the colonic transit function of patients,and can reduce the hemorrhoids within a certain range to prevent the progression of hemorrhoids,thereby comprehensively improving the quality of life of patients.