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慢性肾功能不全对患者认知功能的影响
引用本文:王红,郑淑蓓.慢性肾功能不全对患者认知功能的影响[J].现代中西医结合杂志,2007,16(21):2976-2978.
作者姓名:王红  郑淑蓓
作者单位:温州医学院附属第二医院,浙江,温州,325000
摘    要:目的通过心理测试等手段,探讨慢性肾功能不全对患者认知功能的影响。方法选取40~60岁,性别、文化程度、职业相匹配的临床确诊为慢性肾功能不全的患者和肾功能正常患者各39例,排除可能影响认知功能的各种神经和精神疾病、内分泌疾病、药物和乙醇滥用者,慢性肾功能不全的糖尿病患者需排除曾有严重低血糖发作和酮症酸中毒者,用简易智能状态量表、连线测验和威斯康星卡片分类测验,并测定血液指标进行相关分析,行认知功能的整体评定。结果慢性肾功能不全患者认知功能测验成绩均低于对照组,有显著性差异。结论慢性肾功能不全患者存在着认知能力下降,并且随着肾功能的恶化,这种表现更加明显。

关 键 词:慢性肾功能不全  认知功能  神经心理测试
文章编号:1008-8849(2007)21-2976-03
收稿时间:2006-12-08
修稿时间:2006-12-08

Effect of chronic renal failure on patients' cognitive function
WANG Hong,ZHENG Shu-bei.Effect of chronic renal failure on patients'''' cognitive function[J].Modern Journal of Integrated Chinese Traditional and Western Medicine,2007,16(21):2976-2978.
Authors:WANG Hong  ZHENG Shu-bei
Institution:1. The Second Affiliated Hospital of Wenzhou Medical College, Wenzhou 325000, Zhejiang, China
Abstract:Objective It is to approach the effect of chronic renal failure on the cognitive function of patients by psychological tests, Methods 39 patients with chronic renal failure and 39 normal controls were selected with similar demographic characteristics. And patients with hypoglycemia or ketoacidosis were screened out. Some diseases which might influence cognitive functions were excluded, such as cerebrovascular diseases, cryptorrheic diseases, alcohol and drug abuse, dementia and psychosis. Mini Mental State Examination, Trail Making Test and Wisconsin Card Sorting Task were administered to all groups, And creatinine, urea nitrogen, ferrohemoglobin or electrolure were also analyzed. Results The scores of cognitive tests in patients with chronic renal failure were significantly lower than those in control group. Conclusion Patients with chronic renal failure have some cognitive dysfunction, which is related to the degree of the renal function.
Keywords:chronic renal failure  cognitive function  neuropsychological test
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