4种小鼠的寒、热体质研究

目的研究4种品系小鼠的寒、热体质。方法8～9周龄昆明、BALB/c、C57BL/6J、ICR小鼠,以及4～5周龄昆明小鼠,同步系统检测其生物学特性,然后以统一的评价标准评价4种品系小鼠的寒、热体质。并对BALB/c小鼠给予参桂理中丸和利血平做药物反证。结果①4～5周龄昆明小鼠与8～9周龄昆明小鼠比较体质明显偏热;②BALB/c小鼠与C57BL/6J小鼠比较体质偏寒;③8～9周龄雄性BALB/c小鼠、雄性和雌性C57BL/6J小鼠与8～9周龄相应性别昆明小鼠比较体质无明显差异;8～9周龄雌性BALB/c小鼠与8～9周龄雌性昆明小鼠比较体质偏寒;④8～9周龄ICR小鼠与8～9周龄BALB/c小鼠、C57BL/6J小鼠比较体质偏热;8～9周龄雄性ICR小鼠与8～9周龄雄性昆明小鼠比较体质偏热。结论4种品系小鼠存在寒、热体质差异。

Study of cold or hot constitution in four species of mice

Objective It is to study the cold or hot constitution in four species of mice. Methods Simultaneous systematic inspection about biological characteristics of eight to nine week-old Kunming mice, BALB/c mice, C57BL/6Jmice and ICR mice and four to five week-old Kunming mice were taken, and their cold or hot constitution were assessed with a same criterion. At the same time BALB/c mice were taken drug counterevidence with Shenguilizhong pill and Reserpine. Results ①The constitutions of four to five week-old Kunming mice were more obviously prone to hot compared with eight to nine week-old ones. ②The constitutions of BALB/c mice were prone to cold compared with C57BL/6J mice. ③There was no significant difference in constitution between eight to nine week-old male BALB/c mice and C57BL/6J mice (include male and female) and the same age corresponding sex Kunming mice. The constitutions of eight to nine week-old female BALB/c mice were prone to cold compared with the same age corresponding sex Kunming mice. ④The constitutions of eight to nine week-old ICR mice were prone to hot compared with the same age BALB/c mice and C57BL/6J mice. The constitutions of eight to nine week-old male ICR mice were prone to hot compared with the same age corresponding sex Kunming mice. Conclusion Four species of mice have different cold or hot constitutions.