首页 | 本学科首页   官方微博 | 高级检索  
检索        

香丹注射液对家兔血小板聚集功能的影响
引用本文:仇锦春,廖清船,景霞.香丹注射液对家兔血小板聚集功能的影响[J].现代中药研究与实践,2012(1):42-44.
作者姓名:仇锦春  廖清船  景霞
作者单位:南京医科大学附属南京儿童医院药剂科
摘    要:目的研究香丹注射液对血小板聚集功能的影响。方法进行体内、体外试验,观察香丹注射液对不同诱导剂诱导的家兔血小板聚集率的影响。结果香丹注射液体内能抑制二磷酸腺苷(ADP)、血小板活化因子(PAF)诱导的血小板聚集;体外试验对ADP、PAF诱导的血小板聚集亦有抑制作用,半数抑制浓度(IC50)分别为76.73 mg mL-1、89.21 mg mL-1。结论香丹注射液具有抑制血小板聚集的作用。

关 键 词:香丹注射液  血小板聚集  ADP  PAF

Effects of Xiangdan Injection on Blood Platelet Aggregation Rate of Rabbits
QIU Jin-chun,LIAO Qing-chuan,JING Xia.Effects of Xiangdan Injection on Blood Platelet Aggregation Rate of Rabbits[J].Research and Practice on Chinese Medicines,2012(1):42-44.
Authors:QIU Jin-chun  LIAO Qing-chuan  JING Xia
Institution:(Nanjing Children’s Hospital Affiliated to Nanjing Medical University,Nanjing 210008,China)
Abstract:Objective To study the effects of Xiangdan Injection on blood platelet aggregation rate in vivo and in vitro.Methods The effects of Xiangdan Injection on blood platelet aggregation rate induced by different mutagens in vivo and in vitro were investigated.Results The blood platelet aggregation induced by Adenosine Diphosphate(ADP) and Blood Platelet Activating Factor(PAF) could be inhibited by Xiangdan Injection in vivo and in vitro,and the IC50 value was 76.73 and 89.21 mg mL-1,respectively.Conclusion Xiangdan Injection had obviously suppressing effect to the blood platelet aggregation.
Keywords:Xiangdan Injection  blood platelet aggregation  ADP  PAF
本文献已被 CNKI 维普 等数据库收录!
设为首页 | 免责声明 | 关于勤云 | 加入收藏

Copyright©北京勤云科技发展有限公司  京ICP备09084417号