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| “化斑颗粒剂”对过敏性紫癜模型小鼠网状内皮系统功能的影响 | |
| 引用本文： | 金基成,王雨雁,王荣欣,赵丹阳,李虹,韩冰虹.“化斑颗粒剂”对过敏性紫癜模型小鼠网状内皮系统功能的影响[J].中医药信息,2001,18(6):51-52. |
| 作者姓名： | 金基成 王雨雁 王荣欣 赵丹阳 李虹 韩冰虹 |
| 作者单位： | 1. 黑龙江省中医研究院,黑龙江,哈尔滨,150036 2. 大连市中医医院,辽宁,大连,116013 3. 北京市中西医结合医院,北京,100039 |
| 基金项目： | 黑龙江省自然科学基金资助项目(D00-40) |
| 摘 要： | 过敏性紫癜 (ＨＳＰ)属于免疫复合物 (ＩＣ)介导的全身性小血管炎。其确切的病因尚未完全明确 ,ＨＳＰ发病机制与免疫异常和个体易患有关。现代医学治疗ＨＳＰ尚无切实有效的药物 ,过去常用对症和糖皮质激素治疗 ,经回顾性研究发现其对改善皮肤紫癜和保护肾功没有作用 ,而且它不能缩短疗程、改善预后1 ] ,而中医药治疗ＨＳＰ有很好的优势及前景。 ＨＳＰ属于中医学的“血症”、“紫斑”、“尿血”、“痹证”、“腹痛”、“水肿”等疾病范畴。病理机制多与风热湿毒之邪 ,灼伤脉络 ,迫血妄行等因素密切相关 ,而瘀血内阻贯穿本病全过程。我… |
| 关 键 词： | 过敏性紫癜 网状内皮系统 循环免疫复合物 动物模型 中药治疗 |
| 修稿时间： | 2001年8月10日 |
The influence of Hua Ban powder on reticuloendothelial system of model mouse with allergic purpura |
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| Jin Jicheng,et al Heilongjiang Academy of Traditional Chinese Medicine,Harbin.The influence of Hua Ban powder on reticuloendothelial system of model mouse with allergic purpura[J].Information on Traditional Chinese Medicine,2001,18(6):51-52. | |
| Authors: | Jin Jicheng Heilongjiang Academy of Traditional Chinese Medicine Harbin |
| Institution: | Jin Jicheng,et al Heilongjiang Academy of Traditional Chinese Medicine,Harbin 150036 |
| Abstract: | Objective:observing the effect of "Huaban" granule on REC function and CIC content of mouse with anaphylactoid purpura.Method:Animal model was made by gliadin per.So as antigene and reticuloendothelial system blocked with india-ink,indexes which reflected RES function such as k value,a value and CIC turbity were determinated respectively.Results:The preventive group of "Huaban" granule could enhance model mouses RES function and lower CIC content,this indicated the importance of early and whole cource administration.Conclusion:The mechanism of "Huaban" granule preventing anaphylactoid purpura maybe lowering CIC content and its local deposit by enhancing model mouses RES function and the produce of CIC antigene or the eliminating of CIC. |
| Keywords: | anaphylactoid purpura model mouse reticuloendothelial circulation immune comtlex |
| 本文献已被 CNKI 维普 万方数据 等数据库收录！ | |