黄连、牡丹皮配伍大承气汤对肠热腑实证大鼠IL-6和NO含量的影响

目的:观察黄连、牡丹皮配伍大承气汤对肠热腑实证大鼠IL -6和NO含量的影响.方法:40只大鼠分为正常组、模型组、大承气汤组、HD+大承气汤组,除正常组外,其余大鼠复制肠热腑实证大鼠模型,模型复制成功后,各给药组分别按剂量灌胃14 d,测定IL-6和NO含量.结果:大承气汤组和HD+大承气汤组均能改善大鼠的行为特征和大...

Effects of Berberine and Cortex Moutan Compatible with Dachengqi Decoction on IL -6 and NO of Rats with Intestine-heat and Fu-organ Excess Syndrome

Objective： To observe the effect of berbefine and cortex moutan compatible with Dachengqi Decoction on IL6 and NO of rats with intestine-heat and fu-organ excess syndrome. Method： 40 rats were randomly divided into four groups： normal group, model group, Dchengqi Decoction group and HD ＋ Dachengqi Decoction group. Except for the normal group, the rats in other three groups were copied the models of intestine-heat and fu organ excess syndrome, then the rats in each treatment group were given intestinal perfusion for 14 days to determine the contents of IL -6 and NO. Results： The behavior characteristics and stool condition were improved in both Dchengqi Decoction group and HD ＋ Dachengqi Decoction group, the contents of IL - 6 and NO in both groups were reduced, and HD ＋ Dachengqi Decoction is more effective than Dachengqi Decoction, Conclusion： Berberine and cortex moutan contpatible with Dacbengqi Decoction can be more effective in the treatment of intestine-heat and fu-organ excess syndrome.