温中化萎汤治疗脾虚血瘀型慢性萎缩性胃炎临床研究

目的:观察温中化萎汤治疗脾虚血瘀型慢性萎缩性胃炎的临床疗效。方法:将80例患者随机分为治疗组和对照组,每组各40例。对照组给予摩罗丹浓缩丸,治疗组给予温中化萎汤。观察两组患者的临床疗效,比较两组患者治疗前后症状积分变化情况。结果:治疗组有效率为87.5%,对照组有效率为75.0%,两组患者临床疗效比较,差异具有统计学意义(P0.05)。两组患者治疗后主要症状积分低于治疗前,差异具有统计学意义(P0.05);治疗后治疗组胃脘胀满、饮食减少、胃脘疼痛、疲乏无力、嗳气、反酸嘈杂及舌象积分低于对照组,差异具有统计学意义(P0.05)。两组患者治疗后症状总积分低于治疗前,且治疗组低于对照组,差异具有统计学意义(P0.05)。结论:温中化萎汤治疗脾虚血瘀型慢性萎缩性胃炎疗效显著,可改善患者的临床症状。

Clinical Research on Chronic Atrophic Gastritis with Syndrome of Spleen Deficiency and Blood Stasis Treated with Middle-Warming and Atrophy-Relieving Decoction

Objective:To observe the clinical effects of Middle-Warming and Atrophy-Relieving Decoction on chronic atrophic gastritis with syndrome of spleen deficiency and blood stasis.Methods:Totally 80 patients were randomized into treatment group and control group,40 eases in each group.Control group were given Muo-luo-dan Concentrated Pill while treatment group were given Middle-Warming and Atrophy-Relieving Decoction.The clinical effects of both groups were observed.The changes of the scores of symptoms before and after treatment in both groups were compared.Results:The effective rate was 87.5％ in treatment group and 75.0％ in control group;the difference had statistical significance (P ＜ 0.05).The scores of main symptoms after treatment were lower than those before treatment in both groups;the difference had statistical significance (P ＜ 0.05).The scores of gastric distension,poor appetite,gastric pain,fatigue,belching,acid regurgitation and tongue manifestations in treatment group were lower than these in control group,with statistical difference (P ＜ 0.05).The total scores of symptoms in both groups were lower than those in control group,and treatment group were lower than treatment group,with statistical diffefence (P ＜ 0.05).Conclusion:Middle-Warming and Atrophy-Relieving Decoction has significant therapeutic effects on chronic atrophic gastritis with syndrome of spleen deficiency and blood stasis,which can improve the clinical symptoms of the patients.