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商陆醋炙前后对动物黏膜刺激性比较研究
引用本文:陈琳,吴皓,王媚,史闰均.商陆醋炙前后对动物黏膜刺激性比较研究[J].中国中药杂志,2011,36(7):859-863.
作者姓名:陈琳  吴皓  王媚  史闰均
作者单位:南京中医药大学,药学院,江苏,南京,210029
基金项目:国家中医药管理局公益性行业专项基金项目(200807039)
摘    要:目的:研究商陆醋炙前后对动物黏膜刺激性的变化.方法:采用大鼠和小鼠胃肠道试验及家兔眼结膜刺激性试验,观察商陆醋炙前后对动物黏膜的刺激性变化.结果:经醋制后,商陆对动物黏膜的刺激性显著减弱.结论:醋制法能够降低商陆对动物黏膜的刺激性作用.

关 键 词:商陆  醋制  黏膜刺激性
收稿时间:2010/10/10 0:00:00

Comparative study of mucosa irritation of crude and processed Radix Phytolaccae
CHEN Lin,WU Hao,WANG Mei and SHI Runjun.Comparative study of mucosa irritation of crude and processed Radix Phytolaccae[J].China Journal of Chinese Materia Medica,2011,36(7):859-863.
Authors:CHEN Lin  WU Hao  WANG Mei and SHI Runjun
Institution:Pharmacology College of Nanjing University of Chinese Medicine, Nanjing 210029;Pharmacology College of Nanjing University of Chinese Medicine, Nanjing 210029;Pharmacology College of Nanjing University of Chinese Medicine, Nanjing 210029;Pharmacology College of Nanjing University of Chinese Medicine, Nanjing 210029
Abstract:Objective : To study the changes of mucosa irritation of crude and processed Radix Phytolaccae. Method : Gastrointestinal experiments on rats and mice and the rabbits' eyes irritation experiments were applied to investigate the changes of mucosa irritation of crude and processed Radix Phytolaccae. Result : The mucosa irritation of processed Radix Phytolaccae decreased obviously compared to crude one. Conclusion : After being processed with vinegar, the mucosa irritation on Radix Phytolaccae decreased obviously.
Keywords:Phytolacca acinosa Roxb  processed with vinegar  mucosa irritation
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