中药桔梗的研究进展

桔梗有开宣肺气、祛痰排脓之功效,含有大量的三萜皂苷类成分,为其主要的有效成分,迄今为止共发现39种桔梗皂苷及其苷元,具有显著的镇咳祛痰、抗肿瘤、抗氧化及免疫增强作用,对呼吸系统疾病具有显著的疗效。作者对近10年来国内外有关桔梗的研究情况进行了综述,主要涉及到资源及产地加工、化学成分、质量标准、药理作用以及临床应用等5个方面,分析了桔梗在产地加工方法以及质量标准方面存在的问题,为桔梗的深入研究与应用提供了较为详尽的参考资料。为促进对传统中药的综合开发,有必要深入探讨桔梗的产地加工方法,建立完善的质量标准。

Advances in Studies on Platycodon grandiflorum

Platycodon grandiflorum,as the traditional Chinese medicine,has been employed for dispersing the lung and resolving phlegm soothing the throat,and promoting pus discharge in ancient days.Triterpenoids are its main effective constituents which have dominant activities on antitussive,expectorant,antitumor,antioxidant and immune enhancement.This paper has mainly reviewed the progress of P.grandiflorum on the processing in planting area,chemical constituents,quality standard,pharmacological effects and clinical application in recent ten years,which has provided the important references for its further study,exploitation and application.