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炮制对甘遂、牛膝、苦杏仁特殊毒性及药效的影响
引用本文:聂淑琴,李泽琳,梁爱华,薛宝云,李桂琴,王孝涛.炮制对甘遂、牛膝、苦杏仁特殊毒性及药效的影响[J].中国中药杂志,1996,21(3):153-156.
作者姓名:聂淑琴  李泽琳  梁爱华  薛宝云  李桂琴  王孝涛
作者单位:中国中医研究院中药研究所 北京 100700
摘    要:炮制前后毒理学研究表明,经炮制可降低甘遂、牛膝、苦杏仁对EB病毒早期抗原的激活作用,降低甘遂的皮肤刺激作用、二阶段皮肤肿瘤促进作用及峻泻作用。减毒同时可保留药效或增效。

关 键 词:炮制  特殊毒性  甘遂  牛膝  苦杏仁
收稿时间:1995/5/17 0:00:00

Effects of Processing on Specific Toxicity and Pharmacodynamics of Radix Kansui,Radix Achyranthis Bidentatae and Semen Armeniacae Amarum
Nie Shuqin; Li Zelin; Liang Aihua;Xue Baoyun;Li Guiqin; Wang Xiaotao.Effects of Processing on Specific Toxicity and Pharmacodynamics of Radix Kansui,Radix Achyranthis Bidentatae and Semen Armeniacae Amarum[J].China Journal of Chinese Materia Medica,1996,21(3):153-156.
Authors:Nie Shuqin; Li Zelin; Liang Aihua;Xue Baoyun;Li Guiqin; Wang Xiaotao
Abstract:The comparative toxicological researches on crude and processed drugs show that the activating actionof Radix Kansui,Radix Achyranthis Bidentatae and Semen Armeniacae Amarum on EBV-EA can be decreased by pro-cessing. Processing can also decrease. stimulating activity on mouse skin,inhibit tuinor-pronioting activity in two stageskin tumor promoting test and lapactic effect by Radix Kansui. Meanwhile the pharniacological effects of these drugscan be ratained or increased by processing.
Keywords:processing: specific toxicity  Euphorbia kansui  Achyranthes bidentala  Semen Armeniacae Amarum
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