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金粟兰属植物的化学成分和药理作用研究进展
引用本文:曹聪梅,彭勇,肖培根.金粟兰属植物的化学成分和药理作用研究进展[J].中国中药杂志,2008,33(13):1509-1515.
作者姓名:曹聪梅  彭勇  肖培根
作者单位:中国医学科学院药用植物研究所,北京,100094
基金项目:国家自然科学基金重点项目
摘    要:金粟兰属植物在化学成分和药理作用方面的研究进展进行了综述。金粟兰属植物在民间是治疗肿疖、毒蛇咬伤和跌打损伤的良药,从金粟兰科金粟兰属植物共分离得到68个化合物,化学结构类型包括萜类、香豆素及香豆素苷类、酰胺、有机酸、甾体及甾体皂苷等,其中倍半萜烯类化合物51个。现代药理研究表明金粟兰属植物多具有抗菌、抗肿瘤、增强免疫等活性。目前尚有必要对该属植物的化学成分和药理作用进行深入研究以验证该属植物的民间疗效、探讨该属甚至该科的化学分类学及系统学位置等,从而更好地对其进行开发利用。

关 键 词:金粟兰属  化学成分  倍半萜烯  药理作用
收稿时间:2007/6/18 0:00:00

Advance in on chemical constituent and bioactivity research of genus Chloranthus
CAO Cong-mei; PENG Yong; XIAO Pei-gen.Advance in on chemical constituent and bioactivity research of genus Chloranthus[J].China Journal of Chinese Materia Medica,2008,33(13):1509-1515.
Authors:CAO Cong-mei; PENG Yong; XIAO Pei-gen
Institution:Institute of Medicinal Plant Development, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing 100094, China.
Abstract:Progresses in the studies on chemical constituents and bioactivities of Chloranthus S. were systemically reviewed in this article. The whole plants of most species in Chloranthus have long been used as folk medicine in China for detumescence,treating on snake bite and wound. 68 compounds obtained from the plants in Chloranthus fall into the following compound classes: terpenoids,coumarins,amides,organic acids and sterols. Fifty one sesquiterpenes were got. The results of studies on their bioactivities show that most of the plants in this genus have antibacterial and antitumor activities. Further phytochemical and biological studies on the species in Chloranthus are needed for better medicinal utilization.
Keywords:Chloranthus  chemical constituents  bioactivities
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