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| 委陵菜三萜类化学成分研究 | |
| 引用本文： | 王庆贺,李志勇,沈阳,林厚文,舒薇,周剑斌.委陵菜三萜类化学成分研究[J].中国中药杂志,2006,31(17):1434-1436. |
| 作者姓名： | 王庆贺 李志勇 沈阳 林厚文 舒薇 周剑斌 |
| 作者单位： | 1. 上海交通大学,生命科学技术学院,上海,200246 2. 第二军医大学,长征医院,药学部,上海,200433 3. 第二军医大学,长征医院,闸北分院,药剂科,上海,200070 |
| 摘 要： | 目的：研究委陵菜的化学成分。方法：运用反复硅胶柱色谱及凝胶柱色谱等色谱技术进行分离纯化，根据波谱数据和理化性质进行结构鉴定。结果：分离鉴定了6个化合物，经波谱方法鉴定为3-羟基-11-烯-11，12-脱氢-28，13-乌苏酸内酯(1)，3-O-乙酰坡模醇酸(2)，白桦酸(3)，3-氧代-12-烯-28-乌苏酸(4)，乌苏酸(5)，齐墩果酸(6)。结论：以上化合物均为首次从该植物中分离得到，其中化合物1，2，4为首次从该属中分得。 |
| 关 键 词： | 委陵菜 化学成分 三萜 |
| 文章编号： | 1001-5302（2006）17-1434-03 |
| 收稿时间： | 2005-11-01 |
| 修稿时间： | 2005-11-01 |
Studies on triterpenoids from Potentilla chinensis |
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| WANG Qing-he ;LI Zhi-yong ;SHEN Yang ;LIN Hou-wen ;SHU Wei ;ZHOU Jian-bin.Studies on triterpenoids from Potentilla chinensis[J].China Journal of Chinese Materia Medica,2006,31(17):1434-1436. | |
| Authors: | WANG Qing-he ;LI Zhi-yong ;SHEN Yang ;LIN Hou-wen ;SHU Wei ;ZHOU Jian-bin |
| Institution: | College of Life Science and Biotechnology, Shanghai Jiaotong University, Shanghai 200246, China. |
| Abstract: | Objective: To investigate the chemical constituents of Potentilla chinensis. Method: Silica gel column chromatography and Sephadex LH-20 gel column chromatography were employed for the isolation and purfication. The structures were identified on the basis of spectral data and chemical evidence. Result: Six compounds were isolated and identified as follows: 3-hydroxy-11-ursen-28, 13-olide, 11, 12-dehydroursolic acid lactone (1), 3-O-acetyl pomolic acid (2), betulinic acid (3), 3-oxo-12-ursen-28-oic acid (4), ursolic acid (5), oleanic acid (6). Conclousion: All these compounds were isolated from P. chinensis for the first time, compound 1, 2, 4 were isolated from this genus for the first time. |
| Keywords: | Potentilla chinensis chemical constituents triterpenoid |
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