| 白沙蒿化学成分研究 |
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| 引用本文： | 张杰,李林玺,刘绣华,王勇,赵东保.白沙蒿化学成分研究[J].中国中药杂志,2012,37(2):238-242. |
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| 作者姓名： | 张杰 李林玺 刘绣华 王勇 赵东保 |
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| 作者单位： | 1. 河南大学天然药物与免疫工程省重点实验室,河南开封,475004
2. 河南大学天然药物与免疫工程省重点实验室,河南开封475004;河南大学化学化工学院环境与分析科学研究所,河南开封475004 |
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| 基金项目： | 河南省科技厅科技发展计划项目(092102310282) |
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| 摘 要： | 目的:研究白沙蒿全草的化学成分。方法:采用硅胶、Sephadex LH-20柱色谱等方法对其化学成分进行分离纯化,通过化合物的理化性质和波谱数据鉴定其结构。结果:从白沙蒿全草中分离鉴定了15个化合物,分别为5-羟基-7,4’-二甲氧基二氢黄酮(1),5-羟基-7,4’-二甲氧基黄酮(2),3,5-二羟基-7,4’-二甲氧基二氢黄酮(3),5,3’-二羟基-7,4’-二甲氧基二氢黄酮(4),5,7-二羟基-6,4’-二甲氧基黄酮(5),异野樱素(6),橙皮素(7),柑桔素(8),金合欢素(9),金圣草黄素(10),5,7-二羟基-4’-甲氧基-6,8-二-C-β-葡萄糖苷(11),香蜂草苷(12),金合欢素-7-O-芸香糖苷(13),云杉苷(14),茵陈素(15)。结论:化合物1～3,5,7～8,10～15均为首次从该植物中分离得到。
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| 关 键 词： | 白沙蒿 菊科 蒿属 化学成分 黄酮 |
| 收稿时间： | 2011/6/16 0:00:00 |
Study on chemical constituents of Artemisia sphaerocephala |
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| ZHANG Jie,LI Linxi,LIU Xiuhu,WANG Yong and ZHAO Dongbao.Study on chemical constituents of Artemisia sphaerocephala[J].China Journal of Chinese Materia Medica,2012,37(2):238-242. |
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| Authors: | ZHANG Jie LI Linxi LIU Xiuhu WANG Yong and ZHAO Dongbao |
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| Institution: | Key Laboratory of Natural Medicine and Immuno-Engineering, Henan University, Kaifeng 475004, China;Key Laboratory of Natural Medicine and Immuno-Engineering, Henan University, Kaifeng 475004, China;Key Laboratory of Natural Medicine and Immuno-Engineering, Henan University, Kaifeng 475004, China;Institute of Environmental and Analytical Sciences, College of Chemistry and Chemical Engineering, Henan University, Kaifeng 475004, China;Key Laboratory of Natural Medicine and Immuno-Engineering, Henan University, Kaifeng 475004, China;Institute of Environmental and Analytical Sciences, College of Chemistry and Chemical Engineering, Henan University, Kaifeng 475004, China;Key Laboratory of Natural Medicine and Immuno-Engineering, Henan University, Kaifeng 475004, China;Institute of Environmental and Analytical Sciences, College of Chemistry and Chemical Engineering, Henan University, Kaifeng 475004, China |
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| Abstract: | Further study on the chemical constituents of Artemisia sphaerocephala led to the isolation of fifteen compounds. These compounds were isolated and purified by repeated column chromatography on silica gel and Sephadex LH-20. Their structures were determined by physicochemical properties and spectral data analysis. These compounds were identified as 5-hydroxy-7,4'-dimethoxyflavanone (1), 5-hydroxy-7,4'-dimethoxyflavone (2), 5-hydroxy-7,4'-dimethoxyflavanonol (3), 5,3'-dihydroxy-7,4'-dimethoxyflavanone (4), 5,7-dihydroxy-6,4'-dimethoxyflavone (5), isosakuranetin (6), hesperetin (7), navingenin (8), acacetin (9), chrysoeroil (10), 5,7-dihydroxy-4'-methoxyflavone-6,8-di-C- -glucopyranoside (11), didymin (12), acacetin-7-O-rutinoside (13), piceine (14), and capillarin (15). Compounds 1-3, 5, 7, 8, 10-15 were isolated from this plant for the first time. |
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| Keywords: | Artemisia sphaerocephala Compositae Artemisia chemical constituents flavone |
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