| 白花油麻藤化学成分研究 |
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| 引用本文： | 巩婷,王东晓,刘屏,陈若芸.白花油麻藤化学成分研究[J].中国中药杂志,2010,35(13):1720-1722. |
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| 作者姓名： | 巩婷 王东晓 刘屏 陈若芸 |
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| 作者单位： | 1. 中国医学科学院北京协和医学院药物研究所,北京,100050
2. 中国人民解放军总医院药理研究室,北京,100853 |
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| 基金项目： | 国家自然科学基金项目(30500650) |
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| 摘 要： | 目的:研究白花油麻藤Mucuna birdwoodiana藤茎的化学成分。方法:采用柱色谱方法分离化合物,采用谱学方法鉴定其结构。结果:分离并鉴定了11个化合物。3′-methoxycoumestrol(1),芒柄花素(formononetin,2),染料木素(genisten,3),8-甲雷杜辛(8-O-methylretusin,4),7,3′-二羟基-5′-甲氧基异黄酮(5),大黄酚(chrysophanol,6),丁香脂素(syringaresinol,7),表木栓醇(epifriedelanol,8),羽扇豆醇(lupeol,9)。结论:除化合物2,3,8,9外,以上化合物均为首次从该属植物分得。
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| 关 键 词： | 白花油麻藤 油麻藤属 化学成分 异黄酮 |
| 收稿时间： | 2009/11/4 0:00:00 |
Chemical constituents of stem barks of Mucuna birdwoodiana |
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| GONG Ting,WANG Dongxiao,Liu Ping and CHEN Ruoyun.Chemical constituents of stem barks of Mucuna birdwoodiana[J].China Journal of Chinese Materia Medica,2010,35(13):1720-1722. |
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| Authors: | GONG Ting WANG Dongxiao Liu Ping and CHEN Ruoyun |
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| Institution: | Institute of Materia Medica Chinese Academy of Medical Sciences & Peking Union Medical College Beijing 100050,China;Research Institute for Clinical Pharmacology, General Hospital of PLA, Beijing 100853, China;Research Institute for Clinical Pharmacology, General Hospital of PLA, Beijing 100853, China;Institute of Materia Medica Chinese Academy of Medical Sciences & Peking Union Medical College Beijing 100050,China |
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| Abstract: | Eleven compounds were isolated from the stem bark of Mucuna birdwoodiana. Their structures were elucidated by various spectral analyses and identified as 3'-methoxycoumestrol( 1 ), formononetin( 2 ), genisten( 3 ), 8-O-methylretusin( 4 ), 7, 3'- dihydroxy-5'-methoxyisoflavone( 5 ), chrysophanol( 6 ), syringaresinol( 7 ), epifriedelanol ( 8 ), lupeol( 9 ), respectively. All compounds except 2,3,8 and 9 were isolated from the genus for the first time. |
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| Keywords: | Mucuna birdwoodiana Mucuna contituents isoflavone |
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