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滇黄精化学成分研究
引用本文:王易芬,穆天慧,陈纪军,罗士德.滇黄精化学成分研究[J].中国中药杂志,2003,28(6):524-527.
作者姓名:王易芬  穆天慧  陈纪军  罗士德
作者单位:中国科学院,昆明植物研究所,植物化学与西部植物资源持续利用国家重点实验室,云南,昆明,650204
基金项目:国家自然科学基金 (3 990 873 )
摘    要:目的 :研究滇黄精的化学成分 ,寻找抗HIV活性化合物。方法 :用硅胶柱层析和薄层层析分离 ;用IR ,MS ,NMR等技术鉴定结构。结果 :分离鉴定了 9个化合物 ,分别为甘草素 (1) ,异甘草素 (2 ) ,4′ ,7-二羟基 3′-甲氧基异黄酮 (3) ,(6aR ,11aR) 10-羟基-3,9-二甲氧基紫檀烷 (4) ,4-羟甲基糠醛 (5 ) ,水杨酸 (6 ) ,正丁基-β-D-吡喃果糖苷 (7) ,正丁基-β-D-呋喃果糖苷 (8) ,正丁基-α-D-呋喃果糖苷 (9)。 结论 :化合物 1~ 6为首次从滇黄精中分离得到。

关 键 词:滇黄精  百合科  黄酮  异黄酮  查儿酮  正丁基果糖苷
文章编号:1001-5302(2003)06-0524-04
收稿时间:2002/7/15 0:00:00
修稿时间:2002年7月15日

Studies on Chemical Constituents from the Root of Polygonatum kingianum
WANG Yi-Fen;MU Tian-Hui;CHEN Ji-Jun;LUO Shi-De.Studies on Chemical Constituents from the Root of Polygonatum kingianum[J].China Journal of Chinese Materia Medica,2003,28(6):524-527.
Authors:WANG Yi-Fen;MU Tian-Hui;CHEN Ji-Jun;LUO Shi-De
Institution:State Key Laboratory of Phytochemistry and Plant Resources in West China, Kunming Institute of Botany, Chinese Academy of Sciences, Kunming 650204, Yunnan, China.
Abstract:OBJECTIVE: To investigate the anti-HIV constituents from the root of Polygonatum kingianum. METHOD: The compounds were isolated by column chromatography on silica gel, Sephadex LH-20, MCI-gel CHP-20P and their structures were determined on the basis of their spectroscopic evidence including IR, MS and NMR data. RESULT: 13 compounds were isolated, of which nine compounds were identified as liquiritigenin, isoliquiritigenin, 4', 7-dihydroxy-3'-methoxyisoflavone, (6aR, 11aR)-10-hydroxy-3, 9-dimethoxypterocarpan, 5-hydroxymethyl-2-furancarboxaldehyde, salicylic acid, n-butyl-beta-D-fructopyranoside, n-butyl-beta-D-fructofuranoside, n-butyl-alpha-D-fructofuranoside. CONCLUSION: Compounds 1-6 were obtained from this plant for the first time.
Keywords:Polygonatum kingianum  liliaceae  flavone  isoflavone  chalcone  butylfructoside
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