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基于药性组合的归肾经中药药理作用特征研究
引用本文:任颖龙,顾浩,王耘,乔延江.基于药性组合的归肾经中药药理作用特征研究[J].中国中药杂志,2014,39(13):2413-2416.
作者姓名:任颖龙  顾浩  王耘  乔延江
作者单位:北京中医药大学 中药信息工程研究中心, 北京 100102;北京中医药大学 中药信息工程研究中心, 北京 100102;北京中医药大学 中药信息工程研究中心, 北京 100102;北京中医药大学 中药信息工程研究中心, 北京 100102
基金项目:国家自然科学基金项目(81373985,81173568);教育部新世纪优秀人才支持项目(NECT-11-0605);国家科技支撑计划项目(2008BAI51B01);北京中医药大学科研创新团队支持项目(2011-CXTD-11)
摘    要:进一步明确中药药性与药理作用的关联关系,该文基于药性组合进行了归肾经中药药理作用特征的相关研究。为中药药性理论与药理作用的相互渗透与结合搭建了桥梁。在归肾经中药药性和药理作用研究基础上,通过整理药性、药理作用相关资料,利用关联规则方法,以归肾经药性组合为目标,挖掘得到相关药性组合所对应的药理作用特征。分析发现不同药性组合的归肾经中药在药理作用上存在明显差异,同时也具有共同的药理特征譬如免疫促进等等。研究以不同药性组合的归肾经中药为载体,将中药传统理论与现代研究成果紧密结合,为进一步发展和丰富中药药性理论奠定了基础,同时也为现代医学发展提供了新的视角。

关 键 词:药性组合  药理作用  关联规则
收稿时间:2013/11/27 0:00:00

Study on characteristics of pharmacological effects of traditional Chinese medicines distributing along kidney meridian based on medicinal property combination
REN Ying-long,GU Hao,WANG Yun and QIAO Yan-jiang.Study on characteristics of pharmacological effects of traditional Chinese medicines distributing along kidney meridian based on medicinal property combination[J].China Journal of Chinese Materia Medica,2014,39(13):2413-2416.
Authors:REN Ying-long  GU Hao  WANG Yun and QIAO Yan-jiang
Institution:Information Engineering Research Cencer for Traditional Chinese Medicines, Beijing University of Chinese Medicine, Beijing 100102, China;Information Engineering Research Cencer for Traditional Chinese Medicines, Beijing University of Chinese Medicine, Beijing 100102, China;Information Engineering Research Cencer for Traditional Chinese Medicines, Beijing University of Chinese Medicine, Beijing 100102, China;Information Engineering Research Cencer for Traditional Chinese Medicines, Beijing University of Chinese Medicine, Beijing 100102, China
Abstract:To study the characteristics of pharmacological effects of property combinations of traditional Chinese medicines(TCMs) distributing in the stomach meridian based on medicinal property combination, in order to further define the association relationship between properties of TCMs and their pharmacological effects, and build a bridge for the interpenetration and combination between the medicinal property theory of TCMs and their pharmacological effects. On the basis of the studies on the medicinal property theory of TCMs distributing along the kidney meridian and their pharmacological effects, efforts were made to collect relevant data for medicinal properties and pharmacological effects and mine the characteristics of pharmacological effects that were corresponding to relevant medicinal property combination by processing materials related to medicinal properties and pharmacological effects with the association rules method. According to the analysis, TCMs distributing along the kidney meridian with different medicinal property combinations were significantly differentiated in the pharmacological effects, but shared identical pharmacological effects, such as immunological enhancement. In this study, TCMs distributing along the kidney meridian with different medicinal property combinations were taken as the carriers to closely integrate the traditional Chinese medicine theory with the modern study achievements, lay a solid foundation for further developing and enriching the traditional Chinese medical property theory, while providing a new perspective on the development of modern medicine.
Keywords:medicinal property combination  pharmacological effect  association rules
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