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桑黄化学成分研究
引用本文:莫顺燕,杨永春,石建功.桑黄化学成分研究[J].中国中药杂志,2003,28(4):339-341.
作者姓名:莫顺燕  杨永春  石建功
作者单位:中国医学科学院,中国协和医科大学,药物研究所,北京,100050
基金项目:国家“8 6 3”计划资助项目(2001AA2 34 0 2 1)
摘    要:目的 :对药用真菌桑黄进行化学成分研究。方法 :利用正相硅胶柱层析 ,Al2O3柱层析 ,SephadexLH-20柱层析 ,反相HPLC ,重结晶等分离手段和IR ,MS及 1D ,2DNMR等结构鉴定光谱方法。结果 :从桑黄中分离鉴定了 5个黄酮和两个香豆素类化合物 ,分别为柚皮素、樱花亭、二氢莰非素、7 甲氧基二氢莰非素、北美圣草素、香豆素及莨菪亭。结论 :这些化合物均为首次从针层孔属真菌中发现。

关 键 词:真菌  桑黄  黄酮  香豆素
文章编号:1001-5302(2003)04-0339-03
收稿时间:2002/8/20 0:00:00
修稿时间:2002年8月20日

Studies On Chemical Constitutes of Phellinus igniarius
MO Shun yan;YANG Yong chun;SHI Jian gong.Studies On Chemical Constitutes of Phellinus igniarius[J].China Journal of Chinese Materia Medica,2003,28(4):339-341.
Authors:MO Shun yan;YANG Yong chun;SHI Jian gong
Institution:Institute of Material, Chinese Academy of Medical Sciences, Peking Union Medical College, Beijing 100050, China.
Abstract:Objiedtive:To study the chemical constituents of Phellinus igniarius . Method: Compounds were isolated by nomal phasc sillica gel and Al2O3 chromatography and reverse phase HPLC. Their structures were elucidated by spectroscopic methods including IR, MS and NMR. Result: Five flavonoids and two coumarins were isolated from Phellinus igniarius and their structures were identified as naringenin, sakuranetin, aromadendrin, folerogenin, eriodictyol, coumarin and scopoletin. Conclusion: All these compounds were obtained from this genus for the first time.
Keywords:fungus  Phellinus igniarius  flavonoids  coumarins
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