| 黄芩黄酮类成分抗肿瘤作用及机制研究进展 |
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| 引用本文： | 汤立建,赵良才,李庆林,朱国旗,王训翠.黄芩黄酮类成分抗肿瘤作用及机制研究进展[J].中国中药杂志,2007,32(1):21-23. |
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| 作者姓名： | 汤立建 赵良才 李庆林 朱国旗 王训翠 |
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| 作者单位： | 安徽省现代中药重点实验室,安徽中医学院,药学院,安徽,合肥,230038 |
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| 摘 要： | 黄芩黄酮类成分具有广泛的抗肿瘤活性,药理研究证实通过调节花生四烯酸系统的代谢,抑制肿瘤细胞增殖,诱导细胞凋亡,抑制新生血管生成等作用途径发挥抗肿瘤作用。通过对黄芩黄酮类成分抗肿瘤作用及其机制的文献总结,为中药活性成分的研究提供一定的理论基础。
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| 关 键 词： | 黄芩 黄芩素 黄芩苷 汉黄芩素 抗肿瘤 |
| 文章编号： | 1001-5302（2007）01-0021-03 |
| 收稿时间： | 2006-03-30 |
| 修稿时间： | 2006-03-30 |
Advances in research of antitumor activities and mechanisms of flavonoid compounds in Scutellaria baicalensis |
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| TANG Li-jian;ZHAO Liang-cai;LI Qing-lin;ZHU Guo-qi;WANG Xuncui.Advances in research of antitumor activities and mechanisms of flavonoid compounds in Scutellaria baicalensis[J].China Journal of Chinese Materia Medica,2007,32(1):21-23. |
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| Authors: | TANG Li-jian;ZHAO Liang-cai;LI Qing-lin;ZHU Guo-qi;WANG Xuncui |
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| Institution: | Anhui Key laboratory of Modernized Chinese Material Medica ; School of Pharmacy, Anhui College of Traditional Chinese Medicine, Hefei 230038, China |
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| Abstract: | The flavonoid compounds in Scutellaria baicalensis possess extensive antitumor activities.Pharmacological investigation concluded that they exerted their antineoplastic effect through adjusting metabolic process of arachidonic acid,inhibiting cell growth and angiogenesis,inducing apoptosis in cell lines,etc.The article reviewed the progress in the research of antitumor activities and mechanisms of flavonoid compounds in S.baicalensis furthermore,this article provides theoretical evidences for studying on active constituents in traditional Chinese medicine. |
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| Keywords: | Scutellaria baicalensis baicalein baicalin wogonin antitumor |
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