| 藏药余甘子化学成分研究 |
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| 引用本文： | 张兰珍,赵文华,郭亚健,涂光忠,林树,辛林广.藏药余甘子化学成分研究[J].中国中药杂志,2003,28(10):940-943. |
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| 作者姓名： | 张兰珍 赵文华 郭亚健 涂光忠 林树 辛林广 |
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| 作者单位： | 1. 北京中医药大学,中药学院,北京,100102
2. 北京微量化学研究所,北京,100091 |
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| 基金项目： | 国家自然科学基金项目 (3 9970 93 9) |
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| 摘 要： | 目的 :研究藏药余甘子的化学成分。方法 :各种色谱法分离纯化 ,理化和现代波谱法鉴定结构。结果 :分离鉴定出 11个化合物 ,分别为没食子酸 (Ⅰ ) ,鞣花酸 (Ⅱ ) ,1-O-没食子酰基-β-D-葡萄糖 (Ⅲ ) ,3,6-二-O-没食子酰基-D-葡萄糖 (Ⅳ ) ,诃子酸 (Ⅴ) ,槲皮素 (Ⅵ) ,诃黎勒酸 (Ⅶ) ,鞣云实精 (Ⅷ) ,3-乙基没食子酸 (3-ethoxy-4 ,5-dihydroxy-benzoicacid ,Ⅸ ) ,isostrictiniin(Ⅹ) ,1,6-二-O-没食子酰基-β-D-葡萄糖 (Ⅺ )。 结论 :3 乙基没食子酸 (3-ethoxy-4 ,5-dihydroxy benzoicacid)为一新化合物 ,isostrictiniin为首次从余甘子中得到的化合物。
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| 关 键 词： | 余甘子 多酚 鞣花单宁 3-乙基没食子酸 |
| 文章编号： | 1001-5302(2003)10-0940-04 |
| 收稿时间： | 4/5/2003 12:00:00 AM |
| 修稿时间： | 2003年4月5日 |
Studies on Chemical Constituents in Fruits of Tibetan Medicine Phyllanthus emblica |
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| ZHANG Lan-zhen ;ZHAO Wen-hua ;GUO Ya-jian ;TU Guang-zhong ;LIN Shu ;Xin Lin-guang.Studies on Chemical Constituents in Fruits of Tibetan Medicine Phyllanthus emblica[J].China Journal of Chinese Materia Medica,2003,28(10):940-943. |
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| Authors: | ZHANG Lan-zhen ;ZHAO Wen-hua ;GUO Ya-jian ;TU Guang-zhong ;LIN Shu ;Xin Lin-guang |
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| Institution: | School of Chinese Pharmacy, Beijing University of Traditional Chinese Medicine, Beijing 100102, China. |
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| Abstract: | OBJECTIVE: To investigate the chemical constituents of Tibetan medicine Phyllanthus emblica. METHOD: Various chromatographic techniques were employed for isolation and purification of the constituents, and the structures were elucidated by chemical and spectral analyses. RESULT: 11 compounds were isolated and identified as gallic acid (I), ellagic acid (II), 1-O-galloyl-beta-D-glucose (III), 3,6-di-O-galloyl-D-glucose (IV), chebulinic acid (V), quercetin (VI), chebulagic acid (VII), corilagin (VIII), 3-ethylgallic acid (3-ethoxy-4,5-dihydroxy-benzoic acid, IX), isostrictiniin (X), 1,6-di-O-galloyl-beta-D-glucose (XI). CONCLUSION: 3-Ethylgallic acid (3-ethoxy-4,5-dihydroxy-benzoic acid) is a novel compound, and isostrictiniin was found from P. emblica for the first time. |
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| Keywords: | Phyllanthus emblica polyphenols ellagitannins 3-ethylgallic acid |
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