试论“半仿生提取法”制备中药口服制剂

从生物药剂学的角度设计了“半仿生提取法”制备中药口服制剂的新工艺。即药料先用一定pH的酸水提取,继以一定pH的碱水提取,提取液分别滤过、浓缩、制剂。论述了此种工艺的理论依据,并以芍甘止痛颗粒剂为例介绍该工艺研究的具体做法。

Exploration on Oral Preparations of Chinese Materia Medica by Semi-bionic Extraction

In the light of biopharmacy ,the present new technology to extract oral preparations of Chimese tradi-tional medicinal by semi-bionic method was designed. In the technological process ,the prescribed drugs were decoctedand extracted first in an acid solution with a certain value and then in an alkaline solution with ther pH value. After-wards , the extraers were fihered ,concentrated ,dried and made into preparation. The theoretical basis of this technologywas analyed and the concrete procedures were introduced ,with Shaaogan Zhitong Pill as an example.