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| 中西医结合疗法改善艾滋病合并肺部感染患者中医症候的随机对照研究 | |
| 引用本文： | 岑玉文,谭行华,张坚生,周桂琴,万钢,徐立然,屈冰,孙丽君,蒙志好,陈志海.中西医结合疗法改善艾滋病合并肺部感染患者中医症候的随机对照研究[J].中国中药杂志,2013,38(15):2448-2452. |
| 作者姓名： | 岑玉文 谭行华 张坚生 周桂琴 万钢 徐立然 屈冰 孙丽君 蒙志好 陈志海 |
| 作者单位： | 1. 广州市第八人民医院,广东广州,510060 2. 首都医科大学附属北京地坛医院,北京,100011 3. 河南中医学院第一附属医院,河南郑州,450000 4. 河南省中医药研究院,河南郑州,450004 5. 北京佑安医院,北京,100069 6. 广西壮族自治区龙潭医院,广西柳州,545005 |
| 基金项目： | 国家"艾滋病和病毒性肝炎等重大传染病防治"科技重大专项(2008ZX10005-003) |
| 摘 要： | 目的:为提高疗效,发挥中医药治疗优势,观察比较中西医结合治疗与单纯西医治疗对艾滋病合并肺部感染患者中医症状的影响.方法:采用多中心、分层随机、平行对照的方法,对164例艾滋病合并肺部感染的住院患者分别进行中西医结合治疗和纯西医治疗.参照《中药新药临床研究指导原则》及《11省中医药治疗艾滋病项目临床技术方案(试行)》设计中医证候调查问卷.比较2组治疗方案对中医症状改善的作用.结果:2组病例治疗前基线资料经一致性分析无统计学意义,治疗第28天,中西医结合治疗组中医症候疗效愈显率和无效率分别为44.55％,55.45％,对照组则分别为20.00％,80.00％,经卡方检验中西医结合治疗组症候治愈率和显效率优于纯西医治疗组(P＜0.05),运用广义估计方程对不同访视点2组病例中医症状进行重复测量,结果显示对于但热不寒、头痛2种症状的治疗缓解率中西医结合组优于纯西医组(P=0.022).结论:中西医结合疗法在改善艾滋病合并肺部感染患者的临床症状方面优于单纯西医治疗,尤其对于缓解发热(但热不寒)和头痛2个主要症状上具有明显优势. |
| 关 键 词： | 艾滋病 肺部感染 中西医结合疗法 |
| 收稿时间： | 2013/6/26 0:00:00 |
Randomized controlled study of integrated treatment of traditional Chinese medicine and western medicine on AIDS with pulmonary inflammation patients |
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| CEN Yu-wen,TAN Xing-hu,ZHANG Jian-sheng,ZHOU Gui-qin,WAN Gang,XU Li-ran,QU Bing,SUN Li-jun,MENG Zhi-hao and CHEN Zhi-hai.Randomized controlled study of integrated treatment of traditional Chinese medicine and western medicine on AIDS with pulmonary inflammation patients[J].China Journal of Chinese Materia Medica,2013,38(15):2448-2452. | |
| Authors: | CEN Yu-wen TAN Xing-hu ZHANG Jian-sheng ZHOU Gui-qin WAN Gang XU Li-ran QU Bing SUN Li-jun MENG Zhi-hao and CHEN Zhi-hai |
| Institution: | Guangzhou No.8th People's Hospital, Guangzhou 510060, China;Guangzhou No.8th People's Hospital, Guangzhou 510060, China;Guangzhou No.8th People's Hospital, Guangzhou 510060, China;Affiliated Beijing Ditan Hospital of Capital Medical University, Beijing 100011, China;Affiliated Beijing Ditan Hospital of Capital Medical University, Beijing 100011, China;The First Affiliated Hospital of Henan University of Traditional Chinese Medicine, Zhengzhou 450000, China;Henan Academy of Traditional Chinese Medicine, Zhengzhou 450004, China;Beijing Youan Hospital, Capital Medical University, Beijing 100069, China;Longtan Hospital of Guangxi Province, Liuzhou 545005, China;Affiliated Beijing Ditan Hospital of Capital Medical University, Beijing 100011, China |
| Abstract: | Objective: To compare effects of integrated treatment traditional Chinese medicine and Western medicine(TCM-WM) and simple western medicine on TCM clincal symptoms in the patient of AIDS with pulmonary inflammation. Method: A multicenter randomized controlled trials of 164 subjects evaluated the effects of clinical symptoms of AIDS with pulmonary inflammation of TWO regimens: the TCM-WM group(n=111)and western medicine treatment group(n=53),while incidence of TCM symptoms in different time points in two groups were analyzed. Result: Twenty eight days after treatment,the cured and markedly effective rate of TCM symptoms in the TCM-WM group significantly exceeding that in the western medicine treatment group(cured and markedly effective rate significant efficiency 44.55% vs 20.00%),while the incidence rate for the TCM symptoms of fever and headache in the TCM-WM group was significantly lower than that in western medicine group. Conclusion: The integrated treatment of traditional Chinese medicine and Western medicine helps to alleviate the TCM clinical symptoms of AIDS with pulmonary inflammation. |
| Keywords: | AIDS pulmonary inflammation integrated therapy of traditional Chinese medicine and western medicine |
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