| 银翘散抗流感病毒有效部位群化学成分的分离与鉴定 |
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| 引用本文： | 石钺,石任兵,刘斌,陆蕴如,杜力军.银翘散抗流感病毒有效部位群化学成分的分离与鉴定[J].中国中药杂志,2003,28(1):43-47. |
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| 作者姓名： | 石钺 石任兵 刘斌 陆蕴如 杜力军 |
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| 作者单位： | 1. 清华大学,生命科学院,北京,100084
2. 北京中医药大学,中药学院,北京,100029 |
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| 基金项目： | 国家中医药管理局重点课题 ( 972 0 72 ) |
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| 摘 要： | 目的 :对银翘散抗流感病毒作用的物质基础进行研究。方法 :运用色谱技术进行分离 ,波谱等方法鉴定化合物的结构。结果 :从银翘散抗流感病毒有效部位群中分离得到 11种成分 ,鉴定为牛蒡子苷 (Ⅰ )、连翘苷(Ⅱ )、连翘酯苷 (Ⅲ )、甘草苷 (Ⅳ )、甘草素 (Ⅴ )、染料木素 (Ⅵ )、芒柄花素 (Ⅶ )、大豆素 (Ⅷ )、6 甲氧基大豆素 (Ⅸ )、3,3′ ,4 三甲氧基鞣花酸 (Ⅹ )和绿原酸 (Ⅺ )。结论 :染料木素、大豆素、6 甲氧基大豆素和 3,3′,4 三甲氧基鞣花酸为首次从银翘散群药中获得。
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| 关 键 词： | 银翘散 抗流感病毒 化学成分 |
| 文章编号： | 1001-5302(2003)01-0043-05 |
| 收稿时间： | 2002/3/20 0:00:00 |
| 修稿时间： | 2002年3月20日 |
Isolation and Elucidation of Chemical Constituents with Antiviral Action from Yinqiaosan on Influenza Virus |
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| SHI Yue ;SHI Ren-bing ;LIU Bin ;LU Yun-ru ;DU Li-jun.Isolation and Elucidation of Chemical Constituents with Antiviral Action from Yinqiaosan on Influenza Virus[J].China Journal of Chinese Materia Medica,2003,28(1):43-47. |
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| Authors: | SHI Yue ;SHI Ren-bing ;LIU Bin ;LU Yun-ru ;DU Li-jun |
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| Institution: | School of Life Sciences and Engineering, Tsinghua University, Beijing 100084, China. shiyue1029@hotmail.com |
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| Abstract: | OBJECTIVE: To study the chemical constituents with antiviral action from Yinqiaosan on influenza virus. METHOD: Constituents were isolated by different kinds of column chromatography and their structures were elucidated with chemical and spectral methods. RESULT: Eleven chemical constituents were isolated and elucidated as arctiin, phillyrin, forsythiaside, liquiritigenin, liquiritin, genistein, formononetin, daidzein, glycitrin, 3,3',4-tri-omethlellagic acid and chlorogenic acid. CONCLUSION: Genistein, daidzein, glycitrin and 3,3',4-tri-omethlellagic acid were isolated from Yinqiaosan for the first time. |
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| Keywords: | Yinqiaosan anti-influenza virus chemical constituents |
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