| 四君子汤抗自由基损伤的研究 |
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| 引用本文： | 孙云,龚跃新,李瑞琴,林安平.四君子汤抗自由基损伤的研究[J].中药药理与临床,1992(4). |
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| 作者姓名： | 孙云 龚跃新 李瑞琴 林安平 |
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| 作者单位： | 扬州医学院 225001
(孙云，龚跃新，李瑞琴)，扬州医学院 225001(林安平) |
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| 摘 要： | 本文观察了四君子汤对臭氧(O_3)造成的自由基损伤的实验性衰老模型的影响。结果显示:四君子汤能明显改善衰老模型出现的体力下降、御寒能力和对缺氧的耐受力降低,并降低脂质过氧化物(LPO)含量和脑B型单胺氧化酶(MAO-B)活力,升高血清超氧化物歧化酶(SOD)活力。证明四君子汤具有抗自由基损伤的功能,能延缓衰老。
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| 关 键 词： | 四君子汤 抗自由基损伤 抗衰老 脂质过氧化物 B型单胺氧化酶 超氧化物 歧化酶 |
Pharmacological Research of Si Juln Zi Tang on Antagonising Free Radical Injury |
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| Sun Yun.Pharmacological Research of Si Juln Zi Tang on Antagonising Free Radical Injury[J].Pharmacology and Clinics of Chinese Materia Medica,1992(4). |
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| Authors: | Sun Yun |
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| Abstract: | This article deals with free radical injury model induced by ozone and the anti-aging effect of Si Juin Zi Tang. The results showed that, in model group, physical st~ renth, the ability of cold-resistant and hypoxia-resistant were reduced; the lipid peroxides (LPO) content in plasma, brain, liver and the MAO-B activity of brain were increased; the SOD activity of serum was decreosed as compared witn Model group. these changes were the same with that in old age mice. Si Juin Zi Tang ( 6 , 12g/kg po) could emeliorate these changes induced by ozone. It was shown that Si Juin Zi Tang possessed the effect of antagonising free radical injury. |
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| Keywords: | Si Juin Zi Tang ozone antagonising free radical injury lipid perox ides MAO-B SOD |
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