| 鹿茸磷脂抗衰老的初步研究 |
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| 引用本文： | 徐惠波,李延忠,陈晓光,孙晓波,王本祥.鹿茸磷脂抗衰老的初步研究[J].中药药理与临床,1992(1). |
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| 作者姓名： | 徐惠波 李延忠 陈晓光 孙晓波 王本祥 |
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| 作者单位： | 吉林省中医中药研究院中药所药理室 长春130021
(徐惠波，李延忠，陈晓光，孙晓波)，吉林省中医中药研究院中药所药理室 长春130021(王本祥) |
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| 摘 要： | 灌服鹿茸磷脂,可明显抑制老年小鼠血、脑和肝组织MAO-B活性,降低上述组织中MDA含量,增强脑和肝组织SOD活性,降低心脏脂褐素的含量,增加脑组织RNA和蛋白质含量,并能明显改善小鼠记忆获得障碍。
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| 关 键 词： | 鹿茸磷脂 抗衰老 单胺氧化酶 超氧化物歧化酶 丙二醛 |
Study on the Anti-aging Action of Phosphate of Pilose Antler |
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| Xu- Huibo,Li Yanzong,Chen Xiaoguang,Sun Xiaobo and Wang Benxiang.Study on the Anti-aging Action of Phosphate of Pilose Antler[J].Pharmacology and Clinics of Chinese Materia Medica,1992(1). |
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| Authors: | Xu- Huibo Li Yanzong Chen Xiaoguang Sun Xiaobo and Wang Benxiang |
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| Abstract: | The experiments have demostrated that phosphates isolated from pilose antler (PPPA)could significantly inhibit the activities of MAO-B and reduce the contents of MDA in blood, brain and liver tissues when it was given orally to old mice(24mont-hs-old)for 7 successive days. PPPA could also enhance the SOD activities in liver and brain tissues, and reduce the contents of lipofuscin in heart tissues, and increase the contents of RNA, protein in brain tissues.In addition,PPPA exerted remarkable facilitation action on the acquisition of memory in mice. The results suggested that - PPPA possessed a anti-aging effect. |
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| Keywords: | Phosphate of pilose antler Anti-aging Monoamine oxidase Superoxide dismutase Malondialdehyde |
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