女贞子多糖的免疫调节作用研究

目的：观察女贞子多糖（LAPS）的免疫调节作用。方法：采用环磷酰胺造成小鼠免疫低下模型，观察女贞子多糖对正常及免疫低下小鼠的影响。结果：女贞子多糖对小鼠的免疫作用与机体的免疫状态有关，对非特异性细胞免疫有增强作用，对正常小鼠的特异性细胞免疫无显影响，对免疫抑制状态小鼠的细胞免疫有增强作用。结论：女贞子多糖对小鼠的免疫调节作用与机体的免疫状态有关。

The Study of Ligustrum lucidum polysaccharides on immunoregulation effect in mice

We extracted polysaccharides (LAPS) from Ligustrum lucidum Ait. and investigated the influence of LAPS on immunity in normal and immunosuppressive mice. The result showed that LAPS could enhance the phagocyte activity of peritoneal macrophages in normal and immunosuppressive mice. LAPS had no obvious effects on peripheral blood ANAE lymphocyte ratio in normal mice. But LAPS could increase the ANAE lymphocyte ratio and delayed type hypersensitivity (DTH) reaction in the immunosuppressive mice induced by cyclophosphamide. The result suggested that LAPS had immunopotentiation and immunomodulation on immunity of the mice.