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梭果黄芪的化学成分(英文)
引用本文:孙莉嫚,王晓玲,邓文龙,丁立生,彭树林.梭果黄芪的化学成分(英文)[J].中国天然药物,2011(1):38-41.
作者姓名:孙莉嫚  王晓玲  邓文龙  丁立生  彭树林
作者单位:中国科学院成都生物研究所生态恢复重点实验室;西南民族大学;四川省中医药科学院中药材品质与创新中药四川省重点实验室;
基金项目:四川省科技计划项目(No.07JY029-040); 国家重点基础研究发展计划(973计划,No.2007CB512604)~~
摘    要:目的:研究梭果黄芪根的化学成分。方法:采用硅胶柱色谱、反相Rp-18进行分离纯化,通过理化性质和波谱学数据分析鉴定化合物结构。结果:分离鉴定出10个已知化合物,分别是3-O-β-D-木吡喃糖基-25-O-β-D-葡萄吡喃糖基环黄芪醇(1),异黄芪皂苷Ⅳ(2),环黄芪苷A(3),梭果黄芪苷C(4),2′,4′-二甲氧基-3′-羟基-异黄烷-6-O-β-D-葡萄糖甙(5),毛蕊异黄酮-7-O-β-D-吡喃葡萄糖苷(6),6,4′-二甲氧基-3′-羟基-异黄酮-7-O-β-D-葡萄糖甙(7),β-谷甾醇(8),β-胡萝卜苷(9),6-甲氧基当归素(10)。结论:化合物1-3,5-7,10为首次从该植物中分离得到。

关 键 词:梭果黄芪  环阿屯烷型三萜皂苷  化学成分  

Chemical Constituents from Astragalus ernestii
SUN Li-Man ,WANG Xiao-Ling ,DENG Wen-Long ,DING Li-Sheng ,PENG Shu-Lin ECORES Lab,Chengdu Institute of Biology,Chinese Academy of Sciences,Chengdu,China, Southwest University for Nationalities,Chengdu , Sichuan Key Laboratory of Quality , Innovation Research of Chinese Materia Medica,Sichuan Academy of Chinese Medicine Sciences.Chemical Constituents from Astragalus ernestii[J].Chinese JOurnal of Natural Medicines,2011(1):38-41.
Authors:SUN Li-Man  WANG Xiao-Ling  DENG Wen-Long  DING Li-Sheng  PENG Shu-Lin ECORES Lab  Chengdu Institute of Biology  Chinese Academy of Sciences  Chengdu  China  Southwest University for Nationalities  Chengdu  Sichuan Key Laboratory of Quality  Innovation Research of Chinese Materia Medica  Sichuan Academy of Chinese Medicine Sciences
Institution:SUN Li-Man 1,WANG Xiao-Ling 2,DENG Wen-Long 3,DING Li-Sheng 1,PENG Shu-Lin 1* 1 ECORES Lab,Chengdu Institute of Biology,Chinese Academy of Sciences,Chengdu,610041,China,2 Southwest University for Nationalities,Chengdu 610041,3 Sichuan Key Laboratory of Quality and Innovation Research of Chinese Materia Medica,Sichuan Academy of Chinese Medicine Sciences
Abstract:AIM:To study the chemical constituents of Astragalus ernestii.METHODS:Compounds 1-10 were isolated and purified by silica gel and Rp-18 column chromatography.Their structures were elucidated mainly by spectroscopic methods.RESULTS:Ten known compounds,3-O-β-D-xylopyraosyl-24S-cycloart-3β,6α,16β,24,25-pentaol-25-O-β-D-glucopyranoside (1),isoastragaloside Ⅳ (2),cyclocanthoside A (3),asernestioside C (4),6,3'-dihydroxy-2',4'-dimethoxyisoflavan-6-O-β-D-glucopyranoside (5),calycosin-7-O-β-D-glucoside (6),7,3'-dihydroxyl-6,4'-dimethoxyisoflavon-7-O-β-D-glucopyranoside (7),β-sitosterol (8),β-daucosterol (9),and sphondin (10),were isolated and structurally elucidated.CONCLUSION:Compounds 1-3,5-7 and 10 were isolated from this plant for the first time.
Keywords:Astragalus ernestii  Cycloartane triterpenoid saponin  Chemical constituents  
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