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淡竹叶化学成分研究
引用本文:张靖,王英,张晓琦,张庆文,叶文才.淡竹叶化学成分研究[J].中国天然药物,2009(6):428-431.
作者姓名:张靖  王英  张晓琦  张庆文  叶文才
作者单位:[1]中国药科大学天然药物化学教研室,南京210009 [2]暨南大学中药及天然药物研究所,广州510632 [3]中药药效物质基础及创新药物研究广东省高校重点实验室,广州510632 [4]澳门大学中华医药研究院,广州510632
基金项目:国家杰出青年科学基金(No.30625039);广东省自然科学基金团队项目(No.8351063201000003);澳门特别行政区科学技术发展基金(013/2008/A1)
摘    要:目的:研究淡竹叶(Lophatherum gracile Brongn.)的化学成分。方法:采用各种色谱技术分离纯化,通过理化常数和光谱数据鉴定化合物的结构。结果:从淡竹叶中分离得到14个化合物,其中包括2个黄酮木脂素类成分及7个黄酮类成分,结构分别鉴定为salcolin A(1a)、salcolin B(1b)、苜蓿素(2)、木犀草素(3)、阿福豆苷(4)、苜蓿素7-O-β-D-葡萄糖苷(5)、当药黄素(6)、异荭草苷(7)、苜蓿素7-O-新橙皮糖苷(8)、牡荆素(9)、异牡荆素(10)、对甲氧基肉桂酸(11)、β-谷甾醇(12)和胡萝卜苷(13)。结论:化合物1a,1b,3~4,6~8和10~13均为首次从该植物中分离得到。

关 键 词:淡竹叶  黄酮木脂素  黄酮

Chemical Constituents from the Leaves of Lophatherum gracile
ZHANG Jing,WANG Ying,ZHANG Xiao-Qi,ZHANG Qing-Wen,YE Wen-Cai.Chemical Constituents from the Leaves of Lophatherum gracile[J].Chinese JOurnal of Natural Medicines,2009(6):428-431.
Authors:ZHANG Jing  WANG Ying  ZHANG Xiao-Qi  ZHANG Qing-Wen  YE Wen-Cai
Institution:1Department of Phytochemistry, China Pharmaceutical University, Nanjing 210009; 21nstitute of Traditional Chinese Medicine & Natural Products, Jinan University, Guangzhou 510632; 3Guangdong Province Key Laboratory of Pharmacodynamic Constituents of TCM and New Drugs Research, Jinan University, Guangzhou 510632; 4Institute of Chinese Medical Sciences, University of Macau, China)
Abstract:AIM: To investigate the chemical constituents of the leaves of Lophatherum gracile. METHODS: Isolation and purification were carried out by several column chromatographic methods. Compounds were identified based on their physicochemical properties and spectral data. RESULTS: Fourteen compounds were isolated from the leaves of L. gracile. The structures were elucidated as salcolin A (1a), salcolin B (1b), tricin (2), luteolin (3), afzelin (4), tricin 7-O-β-D-glucopyranoside (5), swertiajaponin (6), isoorientin (7), tricin 7-O-neohesperidoside (8), vitexin (9), isovitexin (10), β-(p-methoxyphenyl) acrylic acid (11), β-sitosterol (12) and daucosterol (13), respectively. CONCLUSION: Compounds 1a, 1b, 3-4, 6-8 and 10-13 were isolated from this plant for the first time.
Keywords:Lophatherum gracile  flavonolignan  flavonoid
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